{"title":"[肾小球免疫病理学:免疫荧光和免疫过氧化物酶的比较研究(作者译)]。","authors":"L M Vieira, E N Sarno, F Ruzany, P R De Lacerda","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In order to evaluate the reliability of immunoperoxidase technic (IP) for immuno-deposits in frozen renal tissue, a single blind study was done comparing it with immunofluorescent technic (IF). Fifty renal biopsies were studied. Ten there were no deposits by IF or IP. In 40 of them the results showed the same specificity and greater intensity for IP. There were 25 cases with IgG, 22 with IgM, 9 with IgA, 3 with Clq, 27 with C3 and 3 with HbsAg. We concluded that IP can be used in place of IF for detection of the immune deposits in renal biopsies and that it offers an easier observation than the later.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 6","pages":"377-81"},"PeriodicalIF":0.0000,"publicationDate":"1979-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Glomerular immunopathology: comparative study with immunofluorescence and immunoperoxidase (author's transl)].\",\"authors\":\"L M Vieira, E N Sarno, F Ruzany, P R De Lacerda\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In order to evaluate the reliability of immunoperoxidase technic (IP) for immuno-deposits in frozen renal tissue, a single blind study was done comparing it with immunofluorescent technic (IF). Fifty renal biopsies were studied. Ten there were no deposits by IF or IP. In 40 of them the results showed the same specificity and greater intensity for IP. There were 25 cases with IgG, 22 with IgM, 9 with IgA, 3 with Clq, 27 with C3 and 3 with HbsAg. We concluded that IP can be used in place of IF for detection of the immune deposits in renal biopsies and that it offers an easier observation than the later.</p>\",\"PeriodicalId\":21265,\"journal\":{\"name\":\"Revista brasileira de pesquisas medicas e biologicas\",\"volume\":\"12 6\",\"pages\":\"377-81\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1979-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista brasileira de pesquisas medicas e biologicas\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista brasileira de pesquisas medicas e biologicas","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Glomerular immunopathology: comparative study with immunofluorescence and immunoperoxidase (author's transl)].
In order to evaluate the reliability of immunoperoxidase technic (IP) for immuno-deposits in frozen renal tissue, a single blind study was done comparing it with immunofluorescent technic (IF). Fifty renal biopsies were studied. Ten there were no deposits by IF or IP. In 40 of them the results showed the same specificity and greater intensity for IP. There were 25 cases with IgG, 22 with IgM, 9 with IgA, 3 with Clq, 27 with C3 and 3 with HbsAg. We concluded that IP can be used in place of IF for detection of the immune deposits in renal biopsies and that it offers an easier observation than the later.
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