氚标记化合物的制备方法

Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362) Pub Date : 1999-06-22 DOI:10.1109/KORUS.1999.876245

I. V. Romannikova, Y. Kit, V. A. Richter, V. Sidorov

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引用次数: 0

摘要

放射性jbellec化合物常用于分子生物学、生态学、药理学、毒理学等不同领域的研究。只有两种放射性同位素(3H和14C)适用于几乎所有有机化合物的标记。由于3H比14C具有更大的理论比活度，所以更倾向于使用3H。但是只有有限数量的氚标记化合物可以在市场上买到。本研究的主要目的是开发一种通用的制备任何有机化合物的方法。

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Method for obtaining of tritium labelled compounds

Introduction Radioactivity -Jbellec compounds are often used in different studies molecular biology, ecology, pharmacology, toxicology, etc. Only two,radioactive isotopes (3H and 14C) is adaptable to labelling of practically all organic compounds. Using of 3H is favoured because it have greater theoretical specific activity in comparison with 14C. But only limited numbers of tritium labelled compounds are commercially available. Development of universal method for preparation of any organic compounds was the main objective of this investigation.

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Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)

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