Tara Kamita Riduana, Isnindar Isnindar, Sri Luliana
{"title":"草甘膦乙醇提取物(Premna serratifolia Linn)的标准化。还有木桩。","authors":"Tara Kamita Riduana, Isnindar Isnindar, Sri Luliana","doi":"10.32382/MF.V17I1.2045","DOIUrl":null,"url":null,"abstract":"Standardization Of Buas Buas Leaf (Premna serrativeolia Linn.) Ethanol Extract And Secang Wood (Caesalpinia sappan Linn.). Extract standardization is a parameter used to ensure the safety and quality of extracts before being developed into pharmaceutical preparations. Meanwhile, Buas buas leaves ( Premna serrativeolia Linn.) are useful for treating gastric disorders, carminatives, hemorrhoids, diuretics, fever, constipation, shortness of breath, and also as anti-inflammatory expectorants, antioxidants, antimicrobials, and anticoagulants. Furthermore,secang wood ( Caesalpinia sappan Linn.) is widely known as a nutritious herbal drink. This research aims to determine extracts standardization including specific parameters (organoleptic and phytochemical screening) and non-specific (drying losses). The multilevel maceration with n-hexane and ethanol solvents extraction method was used. The results showed that the percentage of drying shrinkage in the ethanol extract of buas-buas leaves and secang wood was 18.99% ± 0.60 and 15.27% ± 1.46 respectively. Moreover, the ethanol extract of buas-buas leaves has a thick shape, blackish-brown in color, has a distinctive aromatic odor, while secang wood has a thick, brownish-red color, as well as a distinctive aromatic odor. The Buas buas leaves extract contains flavonoids, phenolics, tannins, saponins, and terpenoids, while secang wood contains only flavonoids, tannins, and terpenoids. Keywords : Extract standardization, Graded maceration, Buas buas leaves, Secang wood. Standarisasi ekstrak merupakan parameter untuk menjamin keamanan dan kualitas ekstrak sebelum dikembangkan menjadi sediaan farmasi. Daun buas-buas ( Premna serratifolia Linn.) berkhasiat sebagai mengobati gangguan lambung, karminatif, diuretik, demam, sesak nafas, ekspektoran antiinflamasi, antioksidan, antimikroba, sembelit, ambeien, dan antikoagulan. Kayu secang ( Caesalpinia sappan Linn.) dikenal sebagai minuman herbal yang berkhasiat. Penelitian ini bertujuan untuk mengetahui standarisasi ekstrak meliputi parameter spesifik (organoleptis dan skrining fitokimia) dan non-spesifik (susut pengeringan). Metode ekstraksi pada penelitian ini menggunakan maserasi bertingkat dengan pelarut n-heksan dan etanol. Hasil penelitian menunjukkan bahwa persentase susut pengeringan ekstrak etanol daun buas-buas sebesar 18,99% ± 0,60 dan ekstrak etanol kayu secang sebesar 15,27% ± 1,46. Ekstrak etanol daun buas-buas memiliki bentuk yang kental, berwarna coklat kehitaman, berbau aromatik khas, sedangkan ekstrak etanol kayu secang memiliki bentuk yang kental, berwarna merah kecoklatan, berbau aromatik khas. Ekstrak etanol daun buas-buas mengandung senyawa flavonoid, fenolik, tanin, saponin, terpenoid. Sementara itu, ekstrak etanol kayu secang mengandung flavonoid, tanin, dan terpenoid. Kata kunci : Standarisasi ekstrak, Maserasi bertingkat, Daun buas-buas, Kayu secang.","PeriodicalId":190256,"journal":{"name":"Media Farmasi","volume":"15 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"STANDARISASI EKSTRAK ETANOL DAUN BUAS-BUAS (Premna serratifolia Linn.) DAN KAYU SECANG (Caesalpinia sappan Linn.).\",\"authors\":\"Tara Kamita Riduana, Isnindar Isnindar, Sri Luliana\",\"doi\":\"10.32382/MF.V17I1.2045\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Standardization Of Buas Buas Leaf (Premna serrativeolia Linn.) Ethanol Extract And Secang Wood (Caesalpinia sappan Linn.). Extract standardization is a parameter used to ensure the safety and quality of extracts before being developed into pharmaceutical preparations. Meanwhile, Buas buas leaves ( Premna serrativeolia Linn.) are useful for treating gastric disorders, carminatives, hemorrhoids, diuretics, fever, constipation, shortness of breath, and also as anti-inflammatory expectorants, antioxidants, antimicrobials, and anticoagulants. Furthermore,secang wood ( Caesalpinia sappan Linn.) is widely known as a nutritious herbal drink. This research aims to determine extracts standardization including specific parameters (organoleptic and phytochemical screening) and non-specific (drying losses). The multilevel maceration with n-hexane and ethanol solvents extraction method was used. The results showed that the percentage of drying shrinkage in the ethanol extract of buas-buas leaves and secang wood was 18.99% ± 0.60 and 15.27% ± 1.46 respectively. Moreover, the ethanol extract of buas-buas leaves has a thick shape, blackish-brown in color, has a distinctive aromatic odor, while secang wood has a thick, brownish-red color, as well as a distinctive aromatic odor. The Buas buas leaves extract contains flavonoids, phenolics, tannins, saponins, and terpenoids, while secang wood contains only flavonoids, tannins, and terpenoids. Keywords : Extract standardization, Graded maceration, Buas buas leaves, Secang wood. Standarisasi ekstrak merupakan parameter untuk menjamin keamanan dan kualitas ekstrak sebelum dikembangkan menjadi sediaan farmasi. Daun buas-buas ( Premna serratifolia Linn.) berkhasiat sebagai mengobati gangguan lambung, karminatif, diuretik, demam, sesak nafas, ekspektoran antiinflamasi, antioksidan, antimikroba, sembelit, ambeien, dan antikoagulan. Kayu secang ( Caesalpinia sappan Linn.) dikenal sebagai minuman herbal yang berkhasiat. Penelitian ini bertujuan untuk mengetahui standarisasi ekstrak meliputi parameter spesifik (organoleptis dan skrining fitokimia) dan non-spesifik (susut pengeringan). Metode ekstraksi pada penelitian ini menggunakan maserasi bertingkat dengan pelarut n-heksan dan etanol. Hasil penelitian menunjukkan bahwa persentase susut pengeringan ekstrak etanol daun buas-buas sebesar 18,99% ± 0,60 dan ekstrak etanol kayu secang sebesar 15,27% ± 1,46. Ekstrak etanol daun buas-buas memiliki bentuk yang kental, berwarna coklat kehitaman, berbau aromatik khas, sedangkan ekstrak etanol kayu secang memiliki bentuk yang kental, berwarna merah kecoklatan, berbau aromatik khas. Ekstrak etanol daun buas-buas mengandung senyawa flavonoid, fenolik, tanin, saponin, terpenoid. Sementara itu, ekstrak etanol kayu secang mengandung flavonoid, tanin, dan terpenoid. Kata kunci : Standarisasi ekstrak, Maserasi bertingkat, Daun buas-buas, Kayu secang.\",\"PeriodicalId\":190256,\"journal\":{\"name\":\"Media Farmasi\",\"volume\":\"15 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-05-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Media Farmasi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32382/MF.V17I1.2045\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Media Farmasi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32382/MF.V17I1.2045","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
摘要
山楂叶标准化(prenna serrativeolia Linn.)乙醇提取物与杉木(Caesalpinia sapan Linn.)。萃取物标准化是保证萃取物在研制成药物制剂前的安全性和质量的一个参数。同时，牛蒡叶(Premna serrativeolia Linn.)可用于治疗胃病、驱风、痔疮、利尿剂、发烧、便秘、呼吸急促，还可作为抗炎祛痰剂、抗氧化剂、抗菌剂和抗凝血剂。此外，苍木(Caesalpinia sappan Linn.)被广泛认为是一种营养丰富的草药饮料。本研究旨在确定提取物的标准化，包括特定参数(感官和植物化学筛选)和非特定参数(干燥损失)。采用正己烷多级浸渍和乙醇溶剂萃取法。结果表明:山楂叶和苍木乙醇提取物的干燥收缩率分别为18.99%±0.60和15.27%±1.46;此外，山核桃叶的乙醇提取物形状厚实，颜色为黑棕色，具有独特的芳香气味，而苍木则具有厚实的棕红色，具有独特的芳香气味。山楂叶提取物含有黄酮类化合物、酚类化合物、单宁、皂苷和萜类化合物，而苍木只含有黄酮类化合物、单宁和萜类化合物。关键词:浸膏标准化，分级浸渍，芦笋叶，苍木标准的定义是:标准的定义是:标准的定义是:标准的定义是:标准的定义是:标准的定义是:标准的定义是:标准的定义是:标准的定义是:丹参(普瑞姆纳·萨瑞特利亚·林恩):柏克沙巴加·孟山都·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉·甘泉Kayu secang (Caesalpinia sappan Linn.)是一种双生植物。Penelitian ini bertujuan untuk mengetahui standarisasekstrak meliputi参数特异性(organoleptis和skrining fitokia)和非特异性(susutpengeringan)。在中国，中国是世界上最受欢迎的国家之一。Hasil penelitian menunjukkan bahwa代表了susupperingan和ekstrak etol的比例为18,99%±0,60，而ekstrak etol的比例为15,27%±1,46。Ekstrak etanol daun buas-buas -buas - memiliki bentuk yang kental, berwarna coklat kehitaman, berbau aromatik khas, sedangkan Ekstrak etanol kayu secang memiliki bentuk yang kental, berwarna merah kecoklatan, berbau aromatik khas。黄酮类化合物、黄酮类化合物、黄酮类化合物、单宁、皂苷、萜类化合物。生葵、白藜芦醇、黄酮类、单宁、丹萜类。Kata kunci: Standarisasi ekstrak, Maserasi bertingkat, Daun buas-buas, Kayu secang。
STANDARISASI EKSTRAK ETANOL DAUN BUAS-BUAS (Premna serratifolia Linn.) DAN KAYU SECANG (Caesalpinia sappan Linn.).
Standardization Of Buas Buas Leaf (Premna serrativeolia Linn.) Ethanol Extract And Secang Wood (Caesalpinia sappan Linn.). Extract standardization is a parameter used to ensure the safety and quality of extracts before being developed into pharmaceutical preparations. Meanwhile, Buas buas leaves ( Premna serrativeolia Linn.) are useful for treating gastric disorders, carminatives, hemorrhoids, diuretics, fever, constipation, shortness of breath, and also as anti-inflammatory expectorants, antioxidants, antimicrobials, and anticoagulants. Furthermore,secang wood ( Caesalpinia sappan Linn.) is widely known as a nutritious herbal drink. This research aims to determine extracts standardization including specific parameters (organoleptic and phytochemical screening) and non-specific (drying losses). The multilevel maceration with n-hexane and ethanol solvents extraction method was used. The results showed that the percentage of drying shrinkage in the ethanol extract of buas-buas leaves and secang wood was 18.99% ± 0.60 and 15.27% ± 1.46 respectively. Moreover, the ethanol extract of buas-buas leaves has a thick shape, blackish-brown in color, has a distinctive aromatic odor, while secang wood has a thick, brownish-red color, as well as a distinctive aromatic odor. The Buas buas leaves extract contains flavonoids, phenolics, tannins, saponins, and terpenoids, while secang wood contains only flavonoids, tannins, and terpenoids. Keywords : Extract standardization, Graded maceration, Buas buas leaves, Secang wood. Standarisasi ekstrak merupakan parameter untuk menjamin keamanan dan kualitas ekstrak sebelum dikembangkan menjadi sediaan farmasi. Daun buas-buas ( Premna serratifolia Linn.) berkhasiat sebagai mengobati gangguan lambung, karminatif, diuretik, demam, sesak nafas, ekspektoran antiinflamasi, antioksidan, antimikroba, sembelit, ambeien, dan antikoagulan. Kayu secang ( Caesalpinia sappan Linn.) dikenal sebagai minuman herbal yang berkhasiat. Penelitian ini bertujuan untuk mengetahui standarisasi ekstrak meliputi parameter spesifik (organoleptis dan skrining fitokimia) dan non-spesifik (susut pengeringan). Metode ekstraksi pada penelitian ini menggunakan maserasi bertingkat dengan pelarut n-heksan dan etanol. Hasil penelitian menunjukkan bahwa persentase susut pengeringan ekstrak etanol daun buas-buas sebesar 18,99% ± 0,60 dan ekstrak etanol kayu secang sebesar 15,27% ± 1,46. Ekstrak etanol daun buas-buas memiliki bentuk yang kental, berwarna coklat kehitaman, berbau aromatik khas, sedangkan ekstrak etanol kayu secang memiliki bentuk yang kental, berwarna merah kecoklatan, berbau aromatik khas. Ekstrak etanol daun buas-buas mengandung senyawa flavonoid, fenolik, tanin, saponin, terpenoid. Sementara itu, ekstrak etanol kayu secang mengandung flavonoid, tanin, dan terpenoid. Kata kunci : Standarisasi ekstrak, Maserasi bertingkat, Daun buas-buas, Kayu secang.
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