莽草酸和奎宁酸在艾姆斯试验中不具有诱变性。

Lloydia Pub Date : 1978-09-01

L B Jacobsen, C L Richardson, H G Floss

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引用次数: 0

摘要

据报道，在小鼠中引起肿瘤的石草酸和其结构类似物奎宁酸都是高等植物中普遍存在的成分，在Ames实验中，当使用和不使用大鼠肝微粒体激活系统时，发现它们不具有诱变性。

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Shikimic acid and quinic acid are not mutagenic in the Ames assay.

Shikimic acid, reported to cause tumors in mice, and its close structural analog, quinic acid, both ubiquitous constituents of higher plants, were found not be be mutagenic in the Ames assay when tested with and without the rat liver microsomal activation system.

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Lloydia

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