急性冠状动脉综合征合并多支冠状动脉疾病患者分步心肌血运重建的结果:裸金属支架置入术后早期行冠状动脉搭桥术

A. V. Bocharov, L. V. Popov
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引用次数: 0

摘要

目的:比较急性冠状动脉综合征裸金属支架置入术后早期行冠状动脉旁路移植术与冠心病患者行冠状动脉旁路移植术的远期疗效。材料和方法。分析急性冠状动脉综合征及多血管病变患者先行临床依赖动脉裸金属支架置入术,90天内行冠状动脉搭桥术的功能性心肌血运重建术,分步治疗24个月的随访结果。结果以正态分布的平均值和标准差(M±SD)表示,非正态分布的中位数以25%和75%的四分位间距表示。定量变量的分布类型通过lilliefors校正Kolmogorov-Smirnov检验进行评估。按照非劣效性标准对支架植入术心肌血运重建术的疗效和安全性进行评价。根据所选的非劣效性设计,使用不良事件差异的双向95%置信区间来估计差异。急性冠状动脉综合征及多血管病变患者使用裸金属支架置入临床依赖动脉后早期的冠状动脉床手术血运重建与冠状动脉搭桥术相当,只是重复血运重建率不同。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE RESULTS OF STEP-BY-STEP MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH ACUTE CORONARY SYNDROME AND MULTIVESSEL CORONARY ARTERY DISEASE: EARLY PERFORMING CORONARY ARTERY BYPASS SURGERY AFTER STENTING USING BARE-METAL STENTS
Objective: To compare the long-term results of coronary artery bypass grafting performed in the early period after stenting for acute coronary syndrome by bare-metal stents with the results of coronary artery bypass grafting in patients with coronary heart disease.Material and Methods. The results of 24-month follow-up of step-by-step treatment of patients with acute coronary syndrome and multivessel lesion who received stenting of clinical-dependent artery with bare-metal stents as the first step and, then, underwent functional myocardial revascularization by aortocoronary bypass surgery within 90 days were analyzed. Results are presented as mean value and standard deviation (M±SD) in case of normal distribution and median with interquartile range in the form of 25 and 75 percentiles in case of non-normal distribution. The type of distribution of quantitative variables was assessed by the Lilliefors-corrected Kolmogorov–Smirnov test. Efficacy and safety assessments were carried out according to the criteria of non-inferiority in comparison with the literature data of myocardial revascularization by stenting. The differences were estimated using a two-way 95% confidence interval of the difference in adverse events based on the selected noninferiority design.Results. Surgical revascularization of the coronary bed in the early period after stenting of the clinically dependent artery using bare-metal stents in patients with acute coronary syndrome and multivessel lesion was equivalent to coronary artery bypass grafting, except for the rate of repeated revascularization.
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