{"title":"Sjögren病严重病程1例","authors":"Marina Leonidovna Kochieva","doi":"10.33920/med-10-2308-06","DOIUrl":null,"url":null,"abstract":"Sjögren's disease is a systemic disease of unknown etiology, a characteristic feature of which is a chronic autoimmune and lymphoproliferative process in the secreting epithelial glands with the development of parenchymatous sialadenitis with xerostomia and dry keratoconjunctivitis with hypolacrimia. Sjögren's syndrome is a lesion of the salivary and lacrimal glands similar to Sjögren's disease, which develops in 5-25% of patients with systemic connective tissue diseases, more often with rheumatoid arthritis, and in 50-75% of patients with chronic autoimmune liver damage (chronic autoimmune hepatitis, primary biliary cirrhosis) and less often in other autoimmune diseases.","PeriodicalId":138653,"journal":{"name":"Spravočnik vrača obŝej praktiki (Journal of Family Medicine)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A case of severe course of Sjögren's disease\",\"authors\":\"Marina Leonidovna Kochieva\",\"doi\":\"10.33920/med-10-2308-06\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Sjögren's disease is a systemic disease of unknown etiology, a characteristic feature of which is a chronic autoimmune and lymphoproliferative process in the secreting epithelial glands with the development of parenchymatous sialadenitis with xerostomia and dry keratoconjunctivitis with hypolacrimia. Sjögren's syndrome is a lesion of the salivary and lacrimal glands similar to Sjögren's disease, which develops in 5-25% of patients with systemic connective tissue diseases, more often with rheumatoid arthritis, and in 50-75% of patients with chronic autoimmune liver damage (chronic autoimmune hepatitis, primary biliary cirrhosis) and less often in other autoimmune diseases.\",\"PeriodicalId\":138653,\"journal\":{\"name\":\"Spravočnik vrača obŝej praktiki (Journal of Family Medicine)\",\"volume\":\"11 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Spravočnik vrača obŝej praktiki (Journal of Family Medicine)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33920/med-10-2308-06\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spravočnik vrača obŝej praktiki (Journal of Family Medicine)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33920/med-10-2308-06","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Sjögren's disease is a systemic disease of unknown etiology, a characteristic feature of which is a chronic autoimmune and lymphoproliferative process in the secreting epithelial glands with the development of parenchymatous sialadenitis with xerostomia and dry keratoconjunctivitis with hypolacrimia. Sjögren's syndrome is a lesion of the salivary and lacrimal glands similar to Sjögren's disease, which develops in 5-25% of patients with systemic connective tissue diseases, more often with rheumatoid arthritis, and in 50-75% of patients with chronic autoimmune liver damage (chronic autoimmune hepatitis, primary biliary cirrhosis) and less often in other autoimmune diseases.