Frequency and severity of symptoms in patients with Fibromyalgia and Migraine

Objectives: to estimate the frequency of migraine in patients with fibromyalgia (FM). Describe and compare clinical characteristics, sociodemographic and severity of FM symptoms, according to presence or absence of migraine. Materials and methods: analytical, observational, cross-sectional study. It included patients over 18 years of age, of both sexes with a diagnosis of FM according to ACR 2010 criteria from a public rheumatology center in Argentina between January 2019 and March 2020. Patients with other concomitant rheumatological diseases were excluded. We used IHS (International Headache Society) criteria for the diagnosis of migraine, FIQ (fibromyalgia Impact Questionnaire) were used to assess severity of symptoms. Results: 59 patients were included, 99% were women. 40.68% of the patients had migraine. In patients with migraine, the median FIQ score was 70.35 (IQR: 63.16-78.76) vs 53.91 (IQR: 37.93-66.05) in the group without migraine, this difference being statistically significant (p<0.01). The multivariate analysis showed a higher FIQ and anxiety score, significantly and independently associated with migraine (OR 1.048, 95% CI 1.005-1.093); OR 1,189, 95% CI 1,033-1,368, respectively). Conclusions: migraine is frequent in patients with FM, and the severity of symptoms and anxiety would be more pronounced in this group of patients.