生物传感器用光学WGM谐振器的研制

I. Brice, A. Pirktina, A. Ubele, K. Grundsteins, A. Atvars, R. Viter, J. Alnis
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引用次数: 6

摘要

窃窃廊模式(WGM)谐振器对附着在表面的纳米粒子非常敏感。我们使用COMSOL Wave Optics模块模拟了这一过程。我们的球形WGM谐振器是通过熔化光纤的尖端产生的,我们测量了105范围内的光学Q因子。在寻找WGM共振谱线位移时,用760nm区域的空气分子氧谱线作为参考标记。我们演示了在WGM微谐振器表面涂覆一层ZnO纳米棒和聚苯乙烯微球。涂层增加了接触面。额外的抗原/抗体层将被涂覆以制造高特异性的生物传感器。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Development of optical WGM resonators for biosensors
Whispering Gallery Mode (WGM) resonators are very sensitive to nanoparticles attaching to the surface. We simulate this process using COMSOL Wave Optics module. Our spherical WGM resonators are produced by melting a tip of an optical fiber and we measure optical Q factors in the 105 range. Molecular oxygen lines of the air in the 760 nm region are used as reference markers when looking for the shifts of the WGM resonance lines. We demonstrate WGM microresonator surface coating with a layer of ZnO nanorods as well as with polystyrene microspheres. Coatings produce increased contact surface. Additional layer of antigens/antibodies will be coated to make high-specificity biosensors.
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