一例罕见的急性t细胞淋巴细胞白血病患儿表现为皮肤受累

Lohit kumar Kalita, C. Kalita, P. Gogoi, U. Sharma
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引用次数: 0

摘要

原发性皮肤受累的t细胞淋巴细胞白血病是罕见的儿童。我们报告一例六岁女童因多发性皮肤病变而入院。她脸色苍白,身体虚弱。全身性淋巴结病变。全血细胞计数显示白细胞计数216,000/mm3。外周血涂片示淋巴母细胞80%。骨髓穿刺显示96%的母细胞具有急性淋巴细胞白血病(T-ALL)的免疫表型和形态学特征,流式细胞术证实了这一点。开始ALL BFM -95缓解诱导治疗方案。细胞毒治疗2个月后,皮肤病变保持不变。症状变得更加严重,她在治疗4个月后死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Rare Case Report of Acute T-cell Lymphoblastic Leukaemia Presenting with Cutaneous Involvement in a Child
Primary cutaneous involvement in T-cell lymphoblastic leukemia is rare in childhood. We present a case of 6-year- old girl admitted to our hospital because of multiple skin lesions. She was looked pale and weak. Generalized lymphadenopathy was present. Complete blood count revealed 216,000/mm3 white blood cell count. Peripheral blood smear showed 80% lymphoblasts. Bone marrow aspiration revealed 96% blastic cells with immunophenotype and morphological characteristics of acute lymphoblastic leukemia (T-ALL) which was confirmed by flowcytometry. ALL BFM -95 remission induction treatment protocol was started. Skin lesion remained same after two month of the cytotoxic therapy. The symptoms became more aggressive and she died after 4 months of treatment.
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