人类免疫缺陷病毒阴性男性淋球菌性尿道炎伴生殖器疣1例

O. Jimoh, J. Ejembi, S. Aliyu, Ibrahim Abdulrasul, T. Mba, A. Olayinka
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引用次数: 0

摘要

淋病在男性和女性中都是一种重要的性传播感染,因此可能导致影响两性的不同并发症。尽管有治疗这种疾病的抗菌剂,但淋病奈瑟菌(NG)的传播仍然很普遍。淋病奈瑟菌对常规使用的抗菌素迅速产生耐药性的能力使其成为一项全球公共卫生挑战。我们报告一位26岁的单身男性,专业人士,他以5周的尿道分泌物和排尿疼痛病史来到我们的诊所。他最初在一家私立医院接受环丙沙星治疗20天,症状没有改善。患者随后来到我们的机构,在实验室检查后,他被诊断为淋病奈瑟菌性尿道炎并接受治疗。药敏试验显示青霉素和环丙沙星耐药NG。然而,由于储存的分离物不能重新激活以进行进一步分析,因此没有进行分子表征。我们提倡对该国性传播感染的综合征管理进行审查,并对NG易感性概况进行全国监测。迫切需要升级实验室设施,以便对性传播感染进行文化和分子鉴定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A case of gonococcal urethritis coexisting with genital warts in a human immunodeficiency virus-negative man
Gonorrhoea is an important sexually transmitted infection in both males and females which could consequently lead to different complications affecting both sexes. Despite availability of antimicrobials to treat the disease, transmission of the agent Neisseria gonorrheae (NG) is still prevalent. The ability of Neisseria gonorrhoeae to rapidly develop resistance to routinely used antimicrobials has made it a global public health challenge. We present a 26 year old single, male, professional who presented to our facility with a five weeks history of urethral discharge and painful micturition. He was initially managed at a private hospital with ciprofloxacin for 20 days with no improvement in symptoms. The patient then presented at our facility where he was diagnosed and managed for Neisseria gonorrhoeae urethritis after laboratory investigations. Susceptibility tests revealed penicillin and ciprofloxacin resistant NG. However, molecular characterization was not done as the stored isolate could not be reactivated for further analysis. We advocate for a review of the syndromic management of STIs in the country and a national surveillance on NG susceptibility profile. There is an urgent need to upgrade laboratory facilities to perform both cultural and molecular identification for sexually transmitted infections.
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