THE COURSE OF SUBCLINICAL SYSTEMIC LYMPHEDEMA OVER A SIX-YEAR PERIOD

The aim of the present study was to evaluate the course of subclinical systemic lymphedema over a six-year period using bioelectrical impedance analysis. A 44-year-old woman sought our clinic six years ago with the complaint of pain and swelling in the legs upon waking that aggravated throughout the course of the day. The physical exam revealed edema in the legs and obesity, with a body mass index (BMI) of 50.6 kg/m2. Bioelectrical impedance analysis was performed and revealed an increase in total intracellular and extracellular water beyond the range of normality. Over a six-year period, the patient lost 12 kilograms and her BMI was lowered, but the pattern of intracellular and extracellular water remained the same. Obesity is associated with an increase in body water characterizing subclinical systemic lymphedema, which is maintained over the years. A reduction in weight may lead to a reduction in the volume of liquids.