赞比亚一只4个月大狗皮肤芽孢菌病的病理和微生物学诊断

J. Yabe, Caesar Luswili, B. Hang'ombe, Katendi Changula, Daniel Ndambasia, Mutinta Mweemba Muwowo, Maron Mubanga, Evans Mulenga
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引用次数: 0

摘要

背景:芽生菌病通常是一种全身性真菌疾病,最常见于狗和人。皮肤受累主要是由于血液传播,但在极少数情况下,可以发生直接接种。病例介绍:本报告描述了一例4个月大的公犬,其皮肤病变由皮炎芽孢菌引起,没有肺部或播散性疾病。通过组织病理学和培养进行诊断。手术减肿联合全身口服伊曲康唑治疗导致病变显著缓解。结论:据作者所知,这是赞比亚报道的第一例皮肤芽孢菌病动物,经口服伊曲康唑成功治疗。犬胚菌病的准确诊断和治疗对公共卫生具有重要意义,因为犬胚菌病可能是人类疾病的预兆。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pathological and Microbiological Diagnosis of Cutaneous Blastomycosis in a Four Months Old Dog in Zambia
Background: Blastomycosis is usually a systemic fungal disease, most commonly diagnosed in dogs and humans. Cutaneous involvement primarily results from hematogenous spread, but in rare cases, direct inoculation can occur. Case presentation: The current report describes a case of a four-month-old male dog presented with cutaneous lesions caused by Blastomyces dermatitidis without the pulmonary or disseminated disease. Diagnosis was achieved through histopathology and culture. Surgical debulking associated with systemic therapy with oral itraconazole resulted in significant remission of the lesion. Conclusions: To the authors' knowledge, this is the first case of cutaneous blastomycosis reported in an animal in Zambia, which was successfully treated using oral itraconazole. Accurate diagnosis and treatment of the disease in dogs is of public health importance as canine blastomycosis can be a presage of the disease in humans.
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