{"title":"同位素交换法制备35s标记有机化合物","authors":"M. F. Barakat, M. El-Banna, A. N. Farag, L. Souka","doi":"10.1080/10256018508623532","DOIUrl":null,"url":null,"abstract":"Isotopic exchange has been applied for the preparation of 35S-labelled methionine, cysteine, dithiooxamide, 2-aminothiazole and sulphanilic acid. On the basis of some preliminary investigations, the suitable conditions for performing the radioactive exchange experiments were identified. Good chemical yields and reasonable radiochemical yields were obtained. The results clearly show that the method is very satisfactory and less laborious as compared to the preparative chemical methods.","PeriodicalId":134489,"journal":{"name":"September 1985","volume":"17 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1985-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Preparation of Some 35S-labelled Organic Compounds by Isotopic Exchange\",\"authors\":\"M. F. Barakat, M. El-Banna, A. N. Farag, L. Souka\",\"doi\":\"10.1080/10256018508623532\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Isotopic exchange has been applied for the preparation of 35S-labelled methionine, cysteine, dithiooxamide, 2-aminothiazole and sulphanilic acid. On the basis of some preliminary investigations, the suitable conditions for performing the radioactive exchange experiments were identified. Good chemical yields and reasonable radiochemical yields were obtained. The results clearly show that the method is very satisfactory and less laborious as compared to the preparative chemical methods.\",\"PeriodicalId\":134489,\"journal\":{\"name\":\"September 1985\",\"volume\":\"17 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1985-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"September 1985\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/10256018508623532\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"September 1985","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/10256018508623532","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Preparation of Some 35S-labelled Organic Compounds by Isotopic Exchange
Isotopic exchange has been applied for the preparation of 35S-labelled methionine, cysteine, dithiooxamide, 2-aminothiazole and sulphanilic acid. On the basis of some preliminary investigations, the suitable conditions for performing the radioactive exchange experiments were identified. Good chemical yields and reasonable radiochemical yields were obtained. The results clearly show that the method is very satisfactory and less laborious as compared to the preparative chemical methods.