同位素交换法制备35s标记有机化合物

M. F. Barakat, M. El-Banna, A. N. Farag, L. Souka
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引用次数: 0

摘要

采用同位素交换法制备了35s标记的蛋氨酸、半胱氨酸、二硫代草酰胺、2-氨基噻唑和磺胺酸。在初步研究的基础上,确定了进行放射性交换实验的适宜条件。得到了良好的化学产率和合理的放射化学产率。结果表明,与制备化学方法相比,该方法是非常令人满意的,而且更省力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preparation of Some 35S-labelled Organic Compounds by Isotopic Exchange
Isotopic exchange has been applied for the preparation of 35S-labelled methionine, cysteine, dithiooxamide, 2-aminothiazole and sulphanilic acid. On the basis of some preliminary investigations, the suitable conditions for performing the radioactive exchange experiments were identified. Good chemical yields and reasonable radiochemical yields were obtained. The results clearly show that the method is very satisfactory and less laborious as compared to the preparative chemical methods.
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