精子细胞陷入困境:瑜伽拯救

V. Dhawan, Rajeev Kumar, N. Malhotra, V. Dadhwal, D. Borthakur, R. Dada
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引用次数: 0

摘要

精子是一种复杂的生物遗传细胞,它不仅被认为是受精时父本基因组传播的载体,而且还被认为是受精后事件的载体。精子分子因子作为最佳胚胎发育和妊娠结局的关键决定因素的贡献已经浮出水面。氧化还原状态、核和线粒体基因组完整性紊乱以及基因表达失调的精子可能影响男性的生育状况,并可能导致胚胎发育受损,增加后代遗传和表观遗传疾病的风险。以瑜伽为基础的生活方式(YBL)作为现代生活方式的一部分的整合已被发现在男性生殖功能紊乱的管理中有益于不孕症和早期妊娠丢失(EPL)患者的痛苦问题。由于不孕症和EPL是具有强烈心身成分的问题,瑜伽的身心干预可能是一种有用的辅助治疗,不仅可以提高精子质量,还可以对生殖潜力、胚胎发生和后代的健康产生积极影响。这篇简短的交流旨在强调父亲因素作为不孕症、EPL的致病因素的重要性,以及整合YBL在此类疾病管理中的有希望的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sperm a cell in distress: Yoga to the rescue
Sperm, one of the complex cells of biological inheritance, are not only considered as mere vectors of transmission of paternal genome at the time of fertilization but also to events post-fertilization. The contribution of sperm molecular factors as a critical determinant of optimal embryonic development and pregnancy outcomes has been brought to surface. Spermatozoa with derangements in redox status, nuclear and mitochondrial genomic integrity, and dysregulated gene expression may affect the fertility status of the male and may result in impaired embryonic development and increase risk of genetic and epigenetic diseases in offspring. The integration of yoga-based lifestyle (YBL) as a part of the modern lifestyle has been found to be beneficial in the management of the derangements in the male reproductive functions in the distressing issue of infertility and early pregnancy loss (EPL) patients. As infertility and EPL are issues with a strong psychosomatic component, yoga a mind body intervention may be a useful adjunctive therapy in the management of these cases and may not only improve the sperm quality but also positively impact the reproductive potential, embryogenesis, and the health of the progeny. This short communication intends to highlight the importance of paternal factors as a causal factor for infertility, EPL, and also the promising role of integration of YBL in the management of such disorders.
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