用于基因分析的集成微加工装置

Digest of Papers. Microprocesses and Nanotechnology '99. 1999 International Microprocesses and Nanotechnology Conference Pub Date : 1999-07-06 DOI:10.1109/IMNC.1999.797475

C. Mastrangelo, M. Burns, D. T. Burke

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引用次数: 14

摘要

由于对廉价遗传信息的需求基本上是无限的，并且分析的成本和时间随着样本量的减少而减少，因此遗传分析是强大的技术驱动因素和小型化技术的优秀候选应用。遗传信息储存在溶液中的长DNA分子中。因此，在微尺度上处理DNA分子需要实现能够处理、混合、热循环、分离和检测纳米和皮升液体样品的微流体装置。本文讨论了用于DNA处理的集成微流控装置的实现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Integrated microfabricated devices for genetic assays

Genetic assays are powerful technology drivers and excellent candidate applications for miniaturization technologies because the demand for inexpensive genetic information is essentially unlimited, and the cost and time for the assay decrease with sample volume. Genetic information is stored in long DNA molecules in solution. Processing of DNA molecules in the microscale hence requires the implementation of microfluidic devices capable of handling, mixing, thermal cycling, separating, and detecting nano and pico liter liquid samples. This paper discusses the implementation of integrated microfluidic devices for DNA processing.

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来源期刊

Digest of Papers. Microprocesses and Nanotechnology '99. 1999 International Microprocesses and Nanotechnology Conference

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