胎粪吸入综合征1例分析

M. Akram Ali S., R. H., R. S., T. Mf, Porkodi M., V. S
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引用次数: 0

摘要

新生儿的第一个大便是胎便。粪是一种粘性物质,由脱落的肠上皮细胞、胆汁酸、羊水、吞下的毛、消化酶、水和粘液组成。产后婴儿更有可能有羊水粪染色(MSAF)。胎粪吸入综合症是新生儿严重疾病和死亡的主要原因,约占新生儿的5%至10%。案例研究:一名新生男婴以足月、真空抽吸、MSAF厚和呼吸窘迫为主诉入住新生儿护理病房,发现胸部和身体背肢皮肤颜色为深绿色。听诊器检查发现呼吸音异常,伴有咕噜声。临床症状包括皮肤颜色,呼吸音和胸片显示胎粪吸入综合征(MAS)的诊断。患者通过鼻腔持续气道正压给予氧气治疗,根据每日体重进行液体管理,入院时给予氨苄西林和庆大霉素等抗生素。建议护理人员采用袋鼠妈妈护理和直接母乳喂养。结论:多年来,新生儿胎粪误吸的用药和护理发生了变化。MAS患者预防性抗生素治疗不会改变患者预后。对于由MAS引起的极端和复发性低氧血症的新生儿,体外膜氧合(ECMO)已被用作最后的治疗手段。然而,仍有一些技术预防和治疗胎粪吸入综合征;因此,研究应继续减少由胎粪吸入综合征引起的疾病和死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Meconium Aspiration Syndrome: Analysis of Case Report
Introduction: The first stool of a newborn child is meconium. Meconium is a sticky material composed of denuded intestinal epithelium cells, bile acid, amniotic fluid, swallowed lanugo hair, digestive enzymes, water and mucus. Post-term infants are more likely to have meconium-stained amniotic fluid (MSAF). Meconium aspiration syndrome, a leading cause of severe illness and death in newborns, occurs in about 5 per cent to 10 per cent of births. Case study: A newborn male baby was admitted to the Neonatal Care Unit with the chief complaints of Term, vacuum extraction and thick MSAF and Respiratory Distress skin colour was found to be dark green in the chest and dorsal limb of the body. Breath sound was found to be abnormal with grunting sounds on examination with a stethoscope. The patient’s Clinical symptoms include the appearance of skin colour, and breath sound and Chest radiography shows the diagnosis of Meconium Aspiration Syndrome (MAS). The patient was treated with O2 through nasal continuous positive airway pressure, fluid management was based on daily body weight and antibiotics like ampicillin and gentamicin was administered at the time of admission. The Patients caretaker was advised to Kangaroo mother care and direct breastfeeding. Conclusion: Over the years, medication and care for newborns with meconium aspiration have evolved and changed. Prophylactic antibiotic therapy in MAS does not change the prognosis of patients. In newborns with extreme and recurrent hypoxemia caused by MAS, extracorporeal membrane oxygenation (ECMO) has been utilised as a last-resort therapy. Nevertheless, there are still several techniques for preventing and treating meconium aspiration syndrome; therefore research should continue to diminish illness and death caused by Meconium aspiration syndrome.
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