缺血性脑卒中并发绒毛膜癌性肺栓塞1例

Sami Himri, M. Labied, G. Lembarki, M. Sabiri, S. Manjra, S. Lezar, F. Essodegui
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引用次数: 0

摘要

绒毛膜癌是一种具有高转移潜力的恶性肿瘤,属于妊娠滋养细胞肿瘤,它可以是生殖细胞起源(非妊娠)或妊娠。绒毛膜癌性肺栓塞是一种罕见且侵袭性的妊娠滋养细胞外疾病,最常发生在正常或病理性妊娠后。其表现与血栓栓塞相似,但其特点是局部浸润和显著的血液播散导致远处转移。人绒毛膜促性腺激素(hCG)水平升高提示诊断。我们报告一例绒毛膜癌肺栓塞累及左肺下叶动脉在44岁的女性患者入院多发性缺血性中风。绒毛膜癌的诊断是在CT扫描中发现高水平的人绒毛膜促性腺激素(hCG),与阴性盆腔成像和既往自然流产史形成对比。化疗后的结果是有利的,这是支持绒毛膜癌诊断的另一个论据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Rare Case of Choriocarcinomatous Pulmonary Embolism revealed by Ischemic Strokes
Choriocarcinoma is a malignant tumor with high metastatic potential belonging to the spectrum of gestational trophoblastic tumors, which can be of germ cell origin (nongestational) or gestational. Choriocarcinomatous pulmonary embolism represents a rare and aggressive extra-gonadal form of gestational trophoblastic disease, most often occurring after a normal or pathological pregnancy. The presentation is similar to that of cruoric embolism, but it is characterized by local invasion and significant hematogenous dissemination leading to distant metastases. Increased Human chorionic gonadotropin hormone (hCG) levels are suggestive of the diagnosis. We report a case of choriocarcinomatous pulmonary embolism involving the inferior lobar artery of the left lung in a 44-year-old female patient admitted for multiple ischemic strokes. The diagnosis of choriocarcinoma was done on CT scan in the presence of high levels of Human chorionic gonadotropin hormone (hCG) contrasting with negative pelvic imaging and a history of previous spontaneous abortion. The outcome was favourable after chemotherapy which was an additional argument in favor of the diagnosis of choriocarcinoma.
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