{"title":"新生儿O/sub 2/和CO/sub 2/解离曲线建模","authors":"E. A. Lynch, T. B. Waggener","doi":"10.1109/NEBC.1991.154585","DOIUrl":null,"url":null,"abstract":"In order to study gas exchange and respiratory control system stability in the newborn period, a model of the O/sub 2/ and CO/sub 2/ dissociation curves is developed which incorporates the changes in hemoglobin with age. The model is a modification of Grodin's equations. The dissociation curves generated by the computer model take into account hematocrit, bicarbonate concentration, pH, barometric pressure, the Bohr effect, the Haldane effect, and the effect of postnatal age on hemoglobin type. They provide improved accuracy in modeling gas exchange and respiratory control system stability in infants.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"105 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Modelling O/sub 2/ and CO/sub 2/ dissociation curves of newborn infants\",\"authors\":\"E. A. Lynch, T. B. Waggener\",\"doi\":\"10.1109/NEBC.1991.154585\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In order to study gas exchange and respiratory control system stability in the newborn period, a model of the O/sub 2/ and CO/sub 2/ dissociation curves is developed which incorporates the changes in hemoglobin with age. The model is a modification of Grodin's equations. The dissociation curves generated by the computer model take into account hematocrit, bicarbonate concentration, pH, barometric pressure, the Bohr effect, the Haldane effect, and the effect of postnatal age on hemoglobin type. They provide improved accuracy in modeling gas exchange and respiratory control system stability in infants.<<ETX>>\",\"PeriodicalId\":434209,\"journal\":{\"name\":\"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference\",\"volume\":\"105 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-04-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/NEBC.1991.154585\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NEBC.1991.154585","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Modelling O/sub 2/ and CO/sub 2/ dissociation curves of newborn infants
In order to study gas exchange and respiratory control system stability in the newborn period, a model of the O/sub 2/ and CO/sub 2/ dissociation curves is developed which incorporates the changes in hemoglobin with age. The model is a modification of Grodin's equations. The dissociation curves generated by the computer model take into account hematocrit, bicarbonate concentration, pH, barometric pressure, the Bohr effect, the Haldane effect, and the effect of postnatal age on hemoglobin type. They provide improved accuracy in modeling gas exchange and respiratory control system stability in infants.<>
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