硬脑膜内静脉窦支架治疗特发性颅内高压患者乳头水肿

Maloney Taylor G, Oros Joseph, G. Reshma, Surujdin Ryan, Gilliland Connor, Hise Joseph H
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引用次数: 0

摘要

导读:最近,一组良性颅内高压患者被发现有脑硬膜静脉狭窄。最近的研究表明,静脉窦支架植入术可以使这些压力正常化,从而解决眼科的问题。方法:将26例因良性颅内高压引起视神经肿胀并发现脑膜静脉窦狭窄的患者转诊至同一医院。这些患者随后接受了脑静脉窦支架置入术。评估手术前后的眼科表现,以及血管内压力测量和支架手术前后的压力梯度。将术前和术后的眼科检查结果以及支架置入前后的术前和术后压力测量结果制成表格。结果:手术前平均压力梯度为13.8 mmHg,支架手术后降至1.3 mmHg。26例患者中有25例在支架术后乳头水肿得到改善。术中及术后无并发症发生。结论:硬脑膜内静脉窦支架置入术是治疗有脑静脉窦狭窄的良性颅内高压的一种安全有效的治疗方法。检查更新和偶尔光学相干断层扫描(OCT)。OCT是一种较新的方法,可以描述视网膜神经纤维层(RNFL)的厚度,该厚度可能在急性IIH病例中增加,或在慢性IIH病例中变薄[3,4]。在自动视野测试中,RNFL变薄与视觉变化相关[5]。这些发现经常发生在有或没有主观视觉改变的球后疼痛患者身上。引用本文:Maloney TG, Oros J, George R等(2021)硬膜内静脉窦支架治疗特发性颅内高压患者乳头水肿。眼外科杂志(1):27-29。眼科外科杂志,2021,4(1):27-29开放获取| Page 28 |我们患者的平均BMI为36.5(范围20.2至62.1)。如果患者既往有硬脑膜静脉窦血栓形成史,通常会发生血管网形成,这就需要在支架部署之前进行血管成形术。作者指出,如果那些有硬膜静脉窦血栓形成史的患者不进行血管成形术,部署的支架通常会有一个狭窄的腰围,这将阻止支架在没有血管成形术的情况下完全扩张。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Endovascular Dural Venous Sinus Stenting for the Treatment of Papilledema in Idiopathic Intracranial Hypertension
Introduction: Recently a subset of patients with Benign Intracranial hypertension has been identified that have cerebral dural venous stenosis. Recent studies have demonstrated that venous sinus stenting can result in normalization of these pressures and resultant resolution of ophthalmologic findings. Methods: Twenty-six patients were referred to a single institution for optic nerve swelling due to Benign Intracranial hypertension and found to have cerebral dural venous sinus stenosis. These patients subsequently underwent cerebral venous sinus stenting. Ophthalmic manifestations were evaluated pre and post procedure as well as intravascular pressure measurements and pressure gradients before and after the stenting procedure. The pre and postoperative ophthalmologic findings were tabulated as well as the pre and post procedure pressure measurements before and after stenting. Results: The average preprocedural pressure gradient measured 13.8 mmHg and was reduced to 1.3 mmHg after the stenting procedure. 25 of 26 patients had improvement in their papilledema after the stenting procedure. No complications occurred during or after the procedure. Conclusion: Endovascular Dural Venous sinus stenting is a safe and effective treatment modality for the ophthalmic manifestations of Benign Intracranial Hypertension in those patients found to have cerebral venous sinus stenosis. Check for updates and occasionally Optical Coherence Tomography (OCT). OCT is a newer methodology that delineates the thickness of the retinal nerve fiber layer (RNFL) which may be increased in acute cases of IIH or demonstrate thinning with chronic cases of IIH [3,4]. Thinning of the RNFL has been correlated with visual changes on automated perimetry testing [5]. These findings frequently occur in the setting of a patient with retrobulbar pain with or without subjective visual changes. Citation: Maloney TG, Oros J, George R, et al. (2021) Endovascular Dural Venous Sinus Stenting for the Treatment of Papilledema in Idiopathic Intracranial Hypertension. J Ophthalmic Surg 4(1):27-29 Maloney TG et al. J Ophthalmic Surg 2021, 4(1):27-29 Open Access | Page 28 | The average BMI of our patient population was 36.5 (range 20.2 to 62.1). If the patient had a history of prior Dural venous sinus thrombosis, web formation often occurred which necessitates angioplasty prior to stent deployment. The authors note that if angioplasty is not performed in those patients with history of dural venous sinus thrombosis, the deployed stent will often have a narrow waist which prevents complete stent expansion without angioplasty.
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