功能性卵巢囊肿:期待治疗与口服避孕药

Mahwish Najam, S. Basheer, Nuzhat Rasheed, Sadia Zahoor
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摘要

背景:卵巢囊肿是育龄女性的常见病。目的:比较口服避孕药对卵巢囊肿的治疗效果。方法:这是一项比较研究,于2017年1月至2018年12月在拉希姆亚尔汗谢赫扎耶德医学院妇产科进行。通过非概率、有目的抽样,共纳入870名女性。获得知情口头同意。超声测量囊肿的大小、部位和特征。采用摇号法将患者分为两组。E组患者给予期待治疗(安慰剂),OC组患者给予激素治疗,联合口服避孕药(COCP),乙炔雌二醇0.03mg,左炔诺孕酮0.15mg。然后对患者进行咨询并随访一个月。一个月后,再次进行USG以衡量囊肿解决的成功程度。收集的数据用SPSS 16进行分析。两组比较是否成功,采用卡方检验,以p值<0.05为显著性。结果:女性平均年龄26.42±7.59岁。已婚女性488人(56%),未婚女性382人(44%)。平均囊肿大小为3.93±1.28cm。605例(69.5%)女性达到了避孕目的,其中259例(59.5%)接受了预期治疗,346例(79.5%)接受了口服避孕药。605例(69.5%)女性成功(囊肿消退),其中259例(59.5%)采用了保守治疗,346例(79.5%)采用了口服避孕药。(p = 0.00)。结论:口服避孕药治疗卵巢囊肿比预期治疗更有效、更成功。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Functional Ovarian cysts: Expectant management versus Oral contraceptives
Background: Ovarian cyst is a common problem in females of reproductive age group. Objective: To compare the expectant management and use of oral contraceptives for the management of ovarian cysts. Methodology: This was a comparative study, conducted in the department of Obstetrics and Gynecology, Sheikh Zayed Medical College, Rahim Yar Khan, from January 2017 to December 2018. A total of 870 females were included through non-probability, purposive sampling. Informed verbal consent was obtained. Ultrasound was performed to measure the cyst size, site, and characteristics. The lottery method was used to divide the patients into two groups. Patients in group E received expectant treatment (placebo) and in group OC, patients were prescribed hormonal treatment with combined oral contraceptive (COCP) having ethinyl estradiol 0.03mg and levonorgestril 0.15mg. Then patients were counseled and followed up for one month. After one month, USG was performed again to measure success as cyst resolution. The collected data was analyzed into SPSS 16. Both groups were compared for success by using the chi-square test, taking p-value <0.05 as significant. Results: Mean age of females was 26.42±7.59 years. There were 488 (56%) married females while 382 (44%) were unmarried. Mean cyst size was 3.93±1.28cm. was achieved in 605 (69.5%) females, out of which 259 (59.5%) had expectant management while 346 (79.5%) had oral contraception. Success (Cyst resolution) was achieved in 605 (69.5%) females, out of which 259 (59.5%) had expectant management while 346 (79.5%) had oral contraception. (p=0.00). Conclusion: It was concluded that oral contraceptives are more effective and successful in the resolution of ovarian cysts as compared to expectant management.
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