COVID-19传播数学模型的教育方法:ode和神经网络

M. Turnea, M. Rotariu, A. Gheorghiță, Fuior Robert, Iustina Condurache
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引用次数: 0

摘要

2019年12月,一种导致呼吸道疾病的特殊冠状病毒首次在中国武汉被发现,并很快在世界范围内传播。即使很少有疫苗被开发出来,实际上它们的效果并没有在几年内对大量人口进行完全的研究,而且这次大流行在未来可能是季节性的,就像流感一样。一种教育工具将有助于学生和研究人员了解疾病传播的模型,特别是对既有传染病知识又有数学建模知识的生物医学工程专业学生。提出了一种针对COVID-19疾病复发波的教育工具。该工具使用两种一般类型的模型:一种可以在普通鉴别疾病(ODE)系统中翻译的隔间模型和神经网络模型。两种模型都考虑了无症状隔离和再感染的可能性。封锁是用几种连续函数来模拟的,而不是用恒定的疾病传播率。构建图形用户界面(GUI),为用户提供直观的方式来学习COVID-19模型。该工具为模型参数的选择提供了可能,为无病和地方病平衡提供了平衡稳定性建议,并计算了基本繁殖数。从保存世界各地病例证据的网站下载了包含少数国家收集数据的预定义集,但用户也可以将新收集的数据加载到工具中以测试模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
AN EDUCATIONAL APPROACH FOR MATHEMATICAL MODELS OF COVID-19 PROPAGATION: ODE AND NEURAL NETWOKS
A special type of coronavirus responsible for respiratory illness was first discovered in Wuhan, China in December 2019 and shortly is spreading in the world. Even few vaccines have been developed, actually their effects are not completely studies during few years over a large population, and it is possible that this pandemic to be seasonal in the future, in a similar manner like the flu. An educational tool will be useful for students and research to learn the model of spreading the disease, especially for biomedical engineering students that have knowledge both about the infectious diseases and mathematical modelling. An educational tool for recurrent waves of COVID-19 disease is proposed. The tool uses two general types of models: a compartment one that can be translated in a system of ordinary differential diseases (ODE) and neural network ones. The asymptomatic compartment and quarantine along with possibility of re-infection is taken into account in both models. The lockdown is simulated using few types of continuous function instead on constant transmission rate of disease. A graphic user interface (GUI) is constructed in order to offer to user an intuitive manner to user learn the COVID-19 models. The tool offers the possibility to choose the parameters of models and suggestion for equilibrium stability to the disease-free and endemic equilibrium and calculation of basic reproduction number. A predefined set with collected data for few countries was downloaded from site that maintains the evidence of cases in the world, but also new collected data by user can be loaded into tool to test the models.
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