Impact of COVID­19 on clinical symptoms in women with genital endometriosis

The objective: to evaluate the psycho-emotional state, lifestyle changes, clinical symptoms and treatment measures in women with genital endometriosis after COVID-19 disease. Materials and methods. The study involved 120 women with genital endometriosis. The main group included 62 women with genital endometriosis after COVID-19 disease, the control group consisted of 58 patients with genital endometriosis, no symptoms of COVID-19 and negative PCR test at the time of examination. Impact of Covid-19 on lifestyle changes, symptoms and treatment of endometriosis was measured with a questionnaire. Pain assessment was performed by a visually analog scale (VAS). The psychoemotional state of women was analyzed by a Peritraumatic Distress Inventory. Statistical analyses based on Microsoft Excel statistical analysis package and “Statistica 7.0”(StatSoft Inc., USA). Results. The scientific work demonstrated high level of peritraumatic stress, lifestyle changes (decreased physical activity, increased sleepiness), worsening of clinical manifestations (increased fatigue, severe menstrual bleeding, dysmenorrhea, increased pelvic pain) and changes in treatment measures (increased analgesics and non-steroidal anti-inflammatory drugs using, discontinuation of hormonal therapy) in women with genital endometriosis after COVID-19 disease compared with group of women with genital endometriosis and without symptoms of coronavirus infection. Conclusions. The obtained results are necessary to optimize the management of patients with genital endometriosis and COVID-19.