脊髓和神经根传导与椎板切除术及不同方法预防兔硬膜外粘连的实验研究

Journal of Modern Clinical Medical Bioengineering Pub Date : 2006-04-30 DOI:10.3760/CMA.J.ISSN.1008-634X.2006.02.005

庞祖才, 李永军, 谭赞全, 许汉权, 谢伟坚, 李文任, 陈棉智, 陈镇秋

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引用次数: 0

摘要

目的探索预防硬膜外粘连的几种方法对脊髓、神经根传导功能的影响.方法40只新西兰白兔随机分为4组.切除L5椎板造成12mm×6mm硬脊膜裸露区,探查神经根.A组注入生理盐水1ml,B组充填高分子量透明质酸钠凝胶1ml,C组用自体L6棘突重建L5椎板,D组用透明质酸钠凝胶充填后再进行L5椎板重建.分别检查术前、术后即刻、术后1、3、6周腓肠肌诱发肌电图,记录M波、H波.结果术后H波潜伏期显著延长,B、D组1周恢复正常,C组3周恢复正常,A组6周恢复正常.M波手术前后潜伏期无明显差异.M波、H波波幅个体差异大,手术前后无明显差异.结论通过测定肌肉动作电位H波潜伏期可灵敏反映神经根、脊髓传导功能;透明质酸钠凝胶能促进脊髓、神经根传导功能的恢复。

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Spinal Cord and Nerve Roots Conduction Implicated by Laminectomy and Various Methods for the Prevention of Epidural Adhesion: An Experimental Study in Rabbits

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Journal of Modern Clinical Medical Bioengineering

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