一种新的基因检测结合医学影像学准确预后和预测癌症类型

F. Shariaty, Lingfeng Duan, V. Pavlov, M. Mousavi, T. Pervunina
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引用次数: 1

摘要

肺癌是世界上导致癌症死亡的最大原因。化疗和放疗对于晚期非小细胞肺癌(NSCLC)患者的预后非常差。肺癌的早期发现是至关重要的,过度的发现延迟或引发肺癌病例可能会导致患者的痛苦,这可能解释了诊断和治疗手术的及时执行和疗效。目前肺癌的治疗方法多基于肿瘤的形态类型,有待进一步研究。这项工作的最终目标是发现新的治疗标记,并使用计算机方法根据CT图像和个体肿瘤遗传组成定制治疗。我们的方法区分腺癌和鳞状细胞癌,帮助医生初步发现肺癌类型。结果,所提出的方法区分这些类型的NSCLC准确率为90%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Novel Gene Assay Combined with Medical Imaging for Accurate Prognosis and Prediction of Cancer Type
Lung cancer is the world's largest cause of cancer mortality. Chemotherapy and radiation have a very poor prognosis for individuals with advanced non-small cell lung cancer (NSCLC). Early identification of lung cancer is critical, and excessive detection delay or triggering lung cancer instances may result in the patient's affliction, which may explain the prompt execution and efficacy of diagnostic and therapeutic operations. Currently, therapeutic methods for lung cancer are based on the morphological type of tumors and require more research. The eventual goal of this work is to discover new markers for therapy and to customize therapy based on CT image and an individual tumor genetic composition using computer methods. Our method distinguishes Adenocarcinoma from Squamous cell carcinoma which helps physicians in initial detection of lung cancer type. As a result, the proposed method distinguished these types of NSCLC by accuracy of 90%.
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