I. Meerovich, I. Kubasova, N. Oborotova, G. Meerovich, S. Demura, A. Brandis, V. Rosenbach‐Belkin, A. Baryshnikov, A. Scherz
{"title":"近红外光敏剂细菌叶绿素丝氨酸的荧光和光动力学性质","authors":"I. Meerovich, I. Kubasova, N. Oborotova, G. Meerovich, S. Demura, A. Brandis, V. Rosenbach‐Belkin, A. Baryshnikov, A. Scherz","doi":"10.1117/12.640051","DOIUrl":null,"url":null,"abstract":"Study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochloriphyllide-serine. The peculiarities of its fluorescence excited by different lasers, dynamics and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue de-oxygenation during tumor irradiation were performed. It was shown that bacteriochloriphyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"486 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine\",\"authors\":\"I. Meerovich, I. Kubasova, N. Oborotova, G. Meerovich, S. Demura, A. Brandis, V. Rosenbach‐Belkin, A. Baryshnikov, A. Scherz\",\"doi\":\"10.1117/12.640051\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochloriphyllide-serine. The peculiarities of its fluorescence excited by different lasers, dynamics and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue de-oxygenation during tumor irradiation were performed. It was shown that bacteriochloriphyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.\",\"PeriodicalId\":219206,\"journal\":{\"name\":\"Current Research on Laser Use in Oncology\",\"volume\":\"486 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Research on Laser Use in Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1117/12.640051\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Research on Laser Use in Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1117/12.640051","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine
Study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochloriphyllide-serine. The peculiarities of its fluorescence excited by different lasers, dynamics and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue de-oxygenation during tumor irradiation were performed. It was shown that bacteriochloriphyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.