The New Strategy in Head and Neck Cancer-Changes in Diagnosis and Survival

The approach for Head and Neck Cancer (HNC) is directly related to the predominance (90%) of Squamous Cell Carcinoma (SCC), where the transition from pre-cancer status to neoplastic clinical lesion is related to stromal inflammation and immune deflection [1]. This focus explain the clinical evolution of the disease and the prognosis without interference of the therapy, where a serie of HPV mucosal viruses determine an oncogenic high risk [2]. Beside the large number of SCC, is mandatory the recognition of a phenothipics changes in these neoplasias, where a great variance of behavior must be considered [3].