氯e6对胸腺细胞质和线粒体膜电位的光动力学作用

G. Gyulkhandanyan
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摘要

跨膜电位似乎是细胞状态敏感的特征,可以提供细胞损伤初期的信息。采用电压敏感染料罗丹明6G研究了光敏剂氯e6对大鼠胸腺淋巴细胞质膜和线粒体膜电位的光动力学作用。研究发现,在细胞光损伤中,线粒体膜电位比质膜电位对膜功能障碍更敏感。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Photodynamic action of chlorin e6 on thymocyte plasmatic and mitochondrial membrane potentials
Transmembrane potentials appear to be cell state sensitive characteristics and can give information about cell damage initial stage. Photodynamic action of the photosensitizer chlorin e6 on plasmatic and mitochondrial membrane potentials of the rat thymus lymphocytes was studied using voltage-sensitive dye rhodamine 6G. It has been revealed that mitochondrial membrane potential is more sensitive characteristic of membrane disfunction than plasmatic one at the cell photodamage.
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