催产素和白细胞介素-14:预测2型糖尿病肾病的新指标

Sumer 1 Pub Date : 2023-08-15 DOI:10.21931/rb/css/2023.08.01.15

Rasha Hasan Jasim, Mohammed Abbas Khulaibus

{"title":"催产素和白细胞介素-14:预测2型糖尿病肾病的新指标","authors":"Rasha Hasan Jasim, Mohammed Abbas Khulaibus","doi":"10.21931/rb/css/2023.08.01.15","DOIUrl":null,"url":null,"abstract":"Diabetes is one of the major risk factors for chronic renal failure (CRF). The present work involved studying the effect of lifestyle factors such as (age, gender,\nsmoking and area of residence) which can affect chronic renal diseases. Also, the\nstudy estimated Oxytocin (Oxt) and Interleukin-14 (IL-14) using the sandwich\nELISA technique in the serum of type 2 diabetic patients with CRF who presented to hemodialysis and a control group. Blood samples of (50) diagnosed type 2\ndiabetic patients with CRF from both sexes were compared with (40) samples\nfrom healthy individuals as a control group. The results demonstrated significant\nelevation (p<0.05) in Oxt and IL-14 concentrations for patients with CRF compared to the control group. As for the subgroups, the statistical test showed a significant difference (p < 0.05) when comparing Oxt levels between the same sex\nin the two groups. While no significant difference was observed when comparing\nIL-14 in the same or the two groups. The parameters Oxt and IL-14 are necessary\ntools for predicting renal failure.\nKeywords: Oxytocin, Interleukin-14, Type 2 Diabetes Mellitus, Hemodialysis","PeriodicalId":443152,"journal":{"name":"Sumer 1","volume":"18 ","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Oxytocin and Interleukin-14: New suggested indicators for prediction of type 2 diabetes-induced nephropathy\",\"authors\":\"Rasha Hasan Jasim, Mohammed Abbas Khulaibus\",\"doi\":\"10.21931/rb/css/2023.08.01.15\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Diabetes is one of the major risk factors for chronic renal failure (CRF). The present work involved studying the effect of lifestyle factors such as (age, gender,\\nsmoking and area of residence) which can affect chronic renal diseases. Also, the\\nstudy estimated Oxytocin (Oxt) and Interleukin-14 (IL-14) using the sandwich\\nELISA technique in the serum of type 2 diabetic patients with CRF who presented to hemodialysis and a control group. Blood samples of (50) diagnosed type 2\\ndiabetic patients with CRF from both sexes were compared with (40) samples\\nfrom healthy individuals as a control group. The results demonstrated significant\\nelevation (p<0.05) in Oxt and IL-14 concentrations for patients with CRF compared to the control group. As for the subgroups, the statistical test showed a significant difference (p < 0.05) when comparing Oxt levels between the same sex\\nin the two groups. While no significant difference was observed when comparing\\nIL-14 in the same or the two groups. The parameters Oxt and IL-14 are necessary\\ntools for predicting renal failure.\\nKeywords: Oxytocin, Interleukin-14, Type 2 Diabetes Mellitus, Hemodialysis\",\"PeriodicalId\":443152,\"journal\":{\"name\":\"Sumer 1\",\"volume\":\"18 \",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sumer 1\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21931/rb/css/2023.08.01.15\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sumer 1","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21931/rb/css/2023.08.01.15","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

糖尿病是慢性肾功能衰竭(CRF)的主要危险因素之一。目前的工作涉及研究生活方式因素的影响，如(年龄、性别、吸烟和居住地区)，这些因素可能影响慢性肾脏疾病。此外，本研究使用三明治helisa技术估计了2型糖尿病合并CRF患者血液透析和对照组血清中的催产素(Oxt)和白细胞介素-14 (IL-14)。将50例诊断为2型糖尿病合并慢性肾功能衰竭的男女患者的血液样本与40例健康个体的血液样本作为对照组进行比较。结果显示，与对照组相比，CRF患者的Oxt和IL-14浓度显著升高(p<0.05)。亚组方面，两组同性间Oxt水平比较，经统计学检验，差异有统计学意义(p < 0.05)。而在同一组或两组中比较il -14无显著差异。Oxt和IL-14参数是预测肾功能衰竭的必要工具。关键词:催产素，白细胞介素-14,2型糖尿病，血液透析

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Oxytocin and Interleukin-14: New suggested indicators for prediction of type 2 diabetes-induced nephropathy

Diabetes is one of the major risk factors for chronic renal failure (CRF). The present work involved studying the effect of lifestyle factors such as (age, gender, smoking and area of residence) which can affect chronic renal diseases. Also, the study estimated Oxytocin (Oxt) and Interleukin-14 (IL-14) using the sandwich ELISA technique in the serum of type 2 diabetic patients with CRF who presented to hemodialysis and a control group. Blood samples of (50) diagnosed type 2 diabetic patients with CRF from both sexes were compared with (40) samples from healthy individuals as a control group. The results demonstrated significant elevation (p<0.05) in Oxt and IL-14 concentrations for patients with CRF compared to the control group. As for the subgroups, the statistical test showed a significant difference (p < 0.05) when comparing Oxt levels between the same sex in the two groups. While no significant difference was observed when comparing IL-14 in the same or the two groups. The parameters Oxt and IL-14 are necessary tools for predicting renal failure. Keywords: Oxytocin, Interleukin-14, Type 2 Diabetes Mellitus, Hemodialysis

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Sumer 1

自引率

0.00%

发文量