红花莲叶和茎提取物的植物化学分析及生物活性研究

Junaidraja Ferozeraj, Muhammed Noufal M P, R. S
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引用次数: 0

摘要

巴西莲子是一种具有较高药用价值的重要草本植物。通过所有这些,几乎所有的部分都用于传统的药物系统。植物中存在的生物活性化合物或植物化学物质具有许多药理活性,如伤口愈合、抗炎、抗肿瘤、镇痛、免疫刺激、抗菌和抗病毒活性。植物化学筛选表明,巴西木叶片甲醇和乙醇提取物中存在酚类和生物碱,巴西木茎提取物中存在生物碱类、黄酮类、甾体、苷类和皂苷等不同成分。采用DPPH法和ABTS法研究其抗氧化活性。采用鸡胚成纤维细胞系体外培养法测定了提取物的创面愈合潜力,发现其茎和叶均表现出创面愈合活性。乙醇提取物在一定时间间隔内表现出较大的伤口愈合潜力。乙醇提取物具有较高的伤口愈合效力。这为今后对该植物进行进一步研究,分离和商业化生产具有伤口愈合特性的植物化学物质铺平了道路。关键词:巴西莲子,抗氧化剂,DPPH和ABTS,伤口愈合,MTT测定
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Phytochemical Analysis and Biological Activities of Alternanthera Braseliana Kuntz Leaves and Stem Extracts
Alternanthera brasiliana Kuntz is an important herb which is having higher medicinal properties. Through all most all of the parts are used in the traditional system of medicines. The bioactive compounds or phytochemicals present in the plant show many pharmacological activities like wound healing, anti-inflammatory, antitumor, analgesic, immunostimulant and, antimicrobial and antiviral activities. Phytochemical screening of methanolic and ethanolic extracts of, A.brasiliana leaves showed the presence of phenol and alkaloids and A.brasiliana stem extracts showed the presence of different constituents like alkaloids flavonoids steroids glycosides and saponin. The DPPH and ABTS methods were followed for studying antioxidant activities of extracts. The wound healing potential of extracts is determined by the in-vitro method by using chick embryo fibroblast cell line study revealed that both stem and leaf showing wound healing activity. From the extracts the ethanolic extracts showing great wound healing potential at a time interval. Ethanolic stem extracts show comparatively higher wound healing potency. This paves way for future studies on this plant for isolation and commercialization of phytochemicals which are responsible for wound healing property of the plant Alternanthera brasiliana Kuntz. Keyword : Alternanthera brasiliana, antioxidant, DPPH and ABTS, wound healing, MTT assay.
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