印度的维生素D缺乏症:加强还是让阳光照进来?

P. Srinivasa, C. Harinarayan
{"title":"印度的维生素D缺乏症:加强还是让阳光照进来?","authors":"P. Srinivasa, C. Harinarayan","doi":"10.15380/2277-5706.JCSR.15.024","DOIUrl":null,"url":null,"abstract":"Vitamin D plays a pivotal role in calcium and mineral metabolism. It is astonishing to find vitamin D deficiency in India despite plentiful sunlight. This could probably because of urbanization, life style and dress code changes, and revision of vitamin D adequacy range. Recent studies in south India using in vitro ampoule model with 7- dehydrocholesterol have shown adequate formation of active form of vitamin D in mid-day sun. In India 70% of populations reside in rural areas. Only 35% of Indian populations have access to regulated milk supply. We as humans can get vitamin D from abundant sunshine, by exposing 18% of body surface area (without sunscreen) to mid-day sun for 30-45 min to cause 1 minimal erythemal dose (MED) which is equivalent to taking about 600 to 1000 IU of vitamin D. This is about the recommended daily dose by expert group on human nutrient requirements and the dose used in studies with fortified milk supplementation studies. Vitamin D synthesized in the skin lasts two-times longer in the body. In populations where there is limited exposure to sunlight, like dress-code limiting sun-exposure, usage of sunscreen with (SPF) greater than 8 etc., vitamin D supplementation may also be required. Since there is widespread calcium deficiency in Indian population, calcium supplementation should be an integral part of vitamin D supplementation therapy.","PeriodicalId":405143,"journal":{"name":"The Journal of Clinical and Scientific Research","volume":"29 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":"{\"title\":\"Vitamin D deficiency in India: Fortify or let the sun shine in?\",\"authors\":\"P. Srinivasa, C. Harinarayan\",\"doi\":\"10.15380/2277-5706.JCSR.15.024\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Vitamin D plays a pivotal role in calcium and mineral metabolism. It is astonishing to find vitamin D deficiency in India despite plentiful sunlight. This could probably because of urbanization, life style and dress code changes, and revision of vitamin D adequacy range. Recent studies in south India using in vitro ampoule model with 7- dehydrocholesterol have shown adequate formation of active form of vitamin D in mid-day sun. In India 70% of populations reside in rural areas. Only 35% of Indian populations have access to regulated milk supply. We as humans can get vitamin D from abundant sunshine, by exposing 18% of body surface area (without sunscreen) to mid-day sun for 30-45 min to cause 1 minimal erythemal dose (MED) which is equivalent to taking about 600 to 1000 IU of vitamin D. This is about the recommended daily dose by expert group on human nutrient requirements and the dose used in studies with fortified milk supplementation studies. Vitamin D synthesized in the skin lasts two-times longer in the body. In populations where there is limited exposure to sunlight, like dress-code limiting sun-exposure, usage of sunscreen with (SPF) greater than 8 etc., vitamin D supplementation may also be required. Since there is widespread calcium deficiency in Indian population, calcium supplementation should be an integral part of vitamin D supplementation therapy.\",\"PeriodicalId\":405143,\"journal\":{\"name\":\"The Journal of Clinical and Scientific Research\",\"volume\":\"29 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Clinical and Scientific Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15380/2277-5706.JCSR.15.024\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Clinical and Scientific Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15380/2277-5706.JCSR.15.024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7

摘要

维生素D在钙和矿物质代谢中起着关键作用。令人惊讶的是,尽管印度阳光充足,但人们却缺乏维生素D。这可能是因为城市化、生活方式和着装规范的改变,以及维生素D充足范围的修订。最近在印度南部使用7-脱氢胆固醇体外安瓿模型的研究表明,在正午的阳光下,维生素D的活性形式充分形成。印度70%的人口居住在农村地区。只有35%的印度人口能够获得受监管的牛奶供应。我们人类可以从充足的阳光中获得维生素D,将18%的体表面积(没有防晒霜)暴露在正午的阳光下30-45分钟,产生1个最小红斑剂量(MED),相当于服用约600至1000国际单位的维生素D。这是人类营养需求专家组推荐的每日剂量,也是强化牛奶补充研究中使用的剂量。在皮肤中合成的维生素D在体内的持续时间是人体的两倍。在阳光照射有限的人群中,如着装要求限制阳光照射,使用SPF大于8的防晒霜等,也可能需要补充维生素D。由于印度人群普遍缺钙,补钙应作为维生素D补充治疗的一个组成部分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vitamin D deficiency in India: Fortify or let the sun shine in?
Vitamin D plays a pivotal role in calcium and mineral metabolism. It is astonishing to find vitamin D deficiency in India despite plentiful sunlight. This could probably because of urbanization, life style and dress code changes, and revision of vitamin D adequacy range. Recent studies in south India using in vitro ampoule model with 7- dehydrocholesterol have shown adequate formation of active form of vitamin D in mid-day sun. In India 70% of populations reside in rural areas. Only 35% of Indian populations have access to regulated milk supply. We as humans can get vitamin D from abundant sunshine, by exposing 18% of body surface area (without sunscreen) to mid-day sun for 30-45 min to cause 1 minimal erythemal dose (MED) which is equivalent to taking about 600 to 1000 IU of vitamin D. This is about the recommended daily dose by expert group on human nutrient requirements and the dose used in studies with fortified milk supplementation studies. Vitamin D synthesized in the skin lasts two-times longer in the body. In populations where there is limited exposure to sunlight, like dress-code limiting sun-exposure, usage of sunscreen with (SPF) greater than 8 etc., vitamin D supplementation may also be required. Since there is widespread calcium deficiency in Indian population, calcium supplementation should be an integral part of vitamin D supplementation therapy.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信