古巴海洋毒素研究概况

C. Alvarez, M. Tejuca, I. Pazos, M. E. Lanio, A. Garateix, A. Aneiros
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引用次数: 3

摘要

近几十年来,古巴的毒素研究在该领域作出了一些重要贡献。对海洋毒素进行的大部分工作都致力于多肽物质的分离、纯化和表征。对这些毒素的纯化、分子和功能特性以及药理学性质进行了修订。所描述的毒素电池包括新的生物分子:毒菌素I和II,来自刺趾草的细胞溶解素;分别从麻花和向日葵中纯化的两种K +通道阻滞剂BgK和ShK;BgII和III是两种Na +通道毒素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Overview of Marine Toxin Research in Cuba
Toxin research in Cuba has made some important contributions to the field in recent decades. Most of the work carried out on marine toxins has been devoted to the isolation, purification, and characterization of polypeptide substances. The purification, molecular, and functional characterization as well as the pharmacological properties of these toxins are revised. The toxin battery described includes new biomolecules: sticholysins I and II, cytolysins from Stichodactyla helianthus; BgK and ShK, two K + channel blockers purified from Bunodosoma granulifera and S. helianthus, respectively; and BgII and III, two Na + channeltoxinsfrom B. granulifera.
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