诱导大鼠克隆神经和胶质细胞分化的超微结构变化。

Neurobiology Pub Date : 1975-03-01

G Klier, D Schubert, S Heinemann

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引用次数: 0

摘要

二丁基腺苷3′-5′单磷酸二丁基腺苷(DBcAMP)诱导克隆大鼠神经和胶质细胞超微结构转变。在DBcAMP存在下培养的细胞在其细长的过程中含有大量排列的微管和微丝，而不含DBcAMP的对照培养相对缺乏这些结构。此外，暴露于DBcAMP的细胞含有2000a至6000a的囊泡，这在对照细胞中没有观察到。

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Ultrastructural changes accompanying the induced differentiation of clonal rat nerve and glia.

Dibutyryladenosine 3'-5' monophosphate (DBcAMP) induces ultrastructural transformations in clonal rat nerve and glia. Cells cultured in the presence of DBcAMP contain large numbers of aligned microtubules and microfilaments in their elongated processes, while control cultures without DBcAMP are relatively devoid of these structures. In addition, the cells exposed to DBcAMP contain 2000 A to 6000 A vesicles which are not observed in control cells.

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Neurobiology

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