肝移植术后急性胰腺炎的研究。

IF 1.1 4区 医学 Q3 SURGERY
Alzbeta Hujova, Peter Macinga, Jana Jarosova, Jiri Fronek, Pavel Taimr, Julius Spicak, Tomas Hucl
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引用次数: 0

摘要

背景:急性胰腺炎(AP)是器官移植后发生的一种相对罕见但严重的并发症。材料和方法本研究的目的是评估单个大容量肝移植中心肝移植术后患者AP的发生率、潜在危险因素和病程。结果:在总共1850例移植患者中,49例(2.8%)被诊断为AP,其中37例(75.5%)为轻度AP, 12例(24.5%)为重度AP。总体死亡率为10%,重度AP组死亡率为42%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Acute Pancreatitis in Patients After Liver Transplantation.

Acute Pancreatitis in Patients After Liver Transplantation.

Acute Pancreatitis in Patients After Liver Transplantation.

Acute Pancreatitis in Patients After Liver Transplantation.

BACKGROUND Acute pancreatitis (AP) is a relatively rare but serious complication that can occur after organ transplantation. MATERIAL AND METHODS The aim of this study was to evaluate the incidence, potential risk factors, and course of AP in patients following liver transplantation at a single large-volume transplant center. RESULTS Out of a total of 1850 transplanted patients, 49 (2.8%) were diagnosed with AP. Of this group, 37 (75.5%) had a mild form of AP and 12 (24.5%) had a severe form of AP. The mortality rate was 10% overall and 42% in the group of patients with severe AP. An early form of AP (<30 days from transplantation) occurred in 13 patients (26.5%), most of whom presented with severe AP (10 patients, 76.9%); 4 patients died (40%). A late form of AP was diagnosed in 36 patients (73.5%), most of whom had mild AP (34 patients, 94.4%); 1 of 2 patients with severe AP died. The most common AP etiologies were post-ERCP (38.8%), idiopathic (34.7%), and postoperative (18.4%). Chronic HBV infection was a risk factor for development of AP (P=0.01). CONCLUSIONS AP in liver transplant recipients was more frequent and more severe than in the general population. This unfavorable course was associated with the occurrence of AP in the early post-transplant period. Liver transplantation due to complications of HBV infection was a risk factor for the development of AP.

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来源期刊
CiteScore
2.50
自引率
0.00%
发文量
79
审稿时长
>12 weeks
期刊介绍: Annals of Transplantation is one of the fast-developing journals open to all scientists and fields of transplant medicine and related research. The journal is published quarterly and provides extensive coverage of the most important advances in transplantation. Using an electronic on-line submission and peer review tracking system, Annals of Transplantation is committed to rapid review and publication. The average time to first decision is around 3-4 weeks. Time to publication of accepted manuscripts continues to be shortened, with the Editorial team committed to a goal of 3 months from acceptance to publication. Expert reseachers and clinicians from around the world contribute original Articles, Review Papers, Case Reports and Special Reports in every pertinent specialty, providing a lot of arguments for discussion of exciting developments and controversies in the field.
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