兽医对SARS-CoV-2有免疫力吗?

IF 1.6 4区 医学 Q4 IMMUNOLOGY
Monika Anna Kozłowska-Geller, Piotr Lewitowicz, Aneta Węgierek-Ciuk, Wioletta Adamus Białek, Agnieszka Piechowska, Stanisław Zbigniew Głuszek
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引用次数: 0

摘要

前言:本研究的目的是评估波兰Świętokrzyskie省兽医中与对照组相比的流行病情况。材料与方法:研究分为3个阶段。第一阶段是选题。在II期,流式细胞术进行免疫表型分型,并评估CD4细胞和CD8细胞亚群的百分比。第三阶段收集鼻咽拭子样本,用rT-PCR法检测犬冠状病毒CR-CoV mRNA。结果:兽医CD4和CD8淋巴细胞亚群占总淋巴细胞群的百分比与对照组的百分比无统计学差异。兽医组CD4/CD8比值平均为1.93,对照组平均为2.04。两组间差异无统计学意义,p = 0.591。在所有兽医和对照组中均未检测到犬CR-CoV mRNA。结论:所有兽医的T淋巴细胞均无明显升高,这可能是对SARS-CoV-2的有效防御。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Could veterinarians be immune to contracting SARS-CoV-2?

Introduction: The aim of the study was to assess the epidemic situation among veterinarians of the Świętokrzyskie Voivodeship, Poland, in relation to the control group.

Material and methods: The research was divided into 3 stages. Stage I involved the selection of subjects. In stage II, flow cytometry for immunophenotyping was performed and the percentage of the sub-population of CD4 cells and CD8 cells was assessed. Stage III involved collection of nasopharyngeal swab samples in order to determine the canine coronavirus CR-CoV mRNA with the rT-PCR method.

Results: The percentage of the CD4 and CD8 lymphocyte subpopulation in relation to the total lymphocyte population in veterinarians did not differ statistically from the percentage in the control group. The CD4/CD8 ratio in the group of veterinarians was on average 1.93, and 2.04 in the control group. There was no statistically significant difference between the groups, p = 0.591. Canine CR-CoV mRNA was not detected in any of the veterinarians or in the control group.

Conclusions: None of the veterinarians had a significant increase in T lymphocytes, which could be an effective defense against SARS-CoV-2.

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来源期刊
CiteScore
3.00
自引率
0.00%
发文量
17
审稿时长
6-12 weeks
期刊介绍: Central European Journal of Immunology is a English-language quarterly aimed mainly at immunologists.
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