Grzegorz Goncerz, Patrycja Kojm, Sylwia Skocelas, Krzysztof Więckowski, Tomasz Gallina, Paulina Pietrzyk, Sebastian Goncerz
{"title":"多喝牛奶与降低骨折风险无关：系统综述和荟萃分析。","authors":"Grzegorz Goncerz, Patrycja Kojm, Sylwia Skocelas, Krzysztof Więckowski, Tomasz Gallina, Paulina Pietrzyk, Sebastian Goncerz","doi":"10.24425/ fmc.2022.144088","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Osteoporosis affects over 200 million people worldwide causing nearly 9 million fractures annually, with more than half in America and Europe.</p><p><strong>Objectives: </strong>This meta-analysis was conducted to investigate whether low milk intake is associated with an increased risk of fractures by summarizing all the available evidence.</p><p><strong>Methods: </strong>Relevant studies were identified by searching the PubMed and EMBASE databases up to June 2020. The pooled relative risks with 95% confidence intervals were calculated.</p><p><strong>Results: </strong>In a meta-regression analysis of 20 included studies (11 cohort and 9 case-control studies), a higher milk intake was not associated with a reduction in the total fracture risk in both sexes (OR 0.95, 95% CI: 0.84- 1.08), either in cohort (OR 0.91; 95% CI: 0.79-1.05) or case-control studies (OR 1.09; 95% CI: 0.82-1.44), as well as separately in men (OR 0.87; 95% CI: 0.71-1.07) and women (OR 0.95; 95% CI: 0.80-1.13).</p><p><strong>Conclusion: </strong>Higher milk consumption is not associated with fracture risk reduction and should not be recommended for fracture prevention.</p>","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"62 4","pages":"137-153"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Higher milk consumption is not associated with fracture risk reduction: systematic review and meta-analysis.\",\"authors\":\"Grzegorz Goncerz, Patrycja Kojm, Sylwia Skocelas, Krzysztof Więckowski, Tomasz Gallina, Paulina Pietrzyk, Sebastian Goncerz\",\"doi\":\"10.24425/ fmc.2022.144088\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Osteoporosis affects over 200 million people worldwide causing nearly 9 million fractures annually, with more than half in America and Europe.</p><p><strong>Objectives: </strong>This meta-analysis was conducted to investigate whether low milk intake is associated with an increased risk of fractures by summarizing all the available evidence.</p><p><strong>Methods: </strong>Relevant studies were identified by searching the PubMed and EMBASE databases up to June 2020. The pooled relative risks with 95% confidence intervals were calculated.</p><p><strong>Results: </strong>In a meta-regression analysis of 20 included studies (11 cohort and 9 case-control studies), a higher milk intake was not associated with a reduction in the total fracture risk in both sexes (OR 0.95, 95% CI: 0.84- 1.08), either in cohort (OR 0.91; 95% CI: 0.79-1.05) or case-control studies (OR 1.09; 95% CI: 0.82-1.44), as well as separately in men (OR 0.87; 95% CI: 0.71-1.07) and women (OR 0.95; 95% CI: 0.80-1.13).</p><p><strong>Conclusion: </strong>Higher milk consumption is not associated with fracture risk reduction and should not be recommended for fracture prevention.</p>\",\"PeriodicalId\":12106,\"journal\":{\"name\":\"Folia medica Cracoviensia\",\"volume\":\"62 4\",\"pages\":\"137-153\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Folia medica Cracoviensia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24425/ fmc.2022.144088\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Folia medica Cracoviensia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24425/ fmc.2022.144088","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Higher milk consumption is not associated with fracture risk reduction: systematic review and meta-analysis.
Introduction: Osteoporosis affects over 200 million people worldwide causing nearly 9 million fractures annually, with more than half in America and Europe.
Objectives: This meta-analysis was conducted to investigate whether low milk intake is associated with an increased risk of fractures by summarizing all the available evidence.
Methods: Relevant studies were identified by searching the PubMed and EMBASE databases up to June 2020. The pooled relative risks with 95% confidence intervals were calculated.
Results: In a meta-regression analysis of 20 included studies (11 cohort and 9 case-control studies), a higher milk intake was not associated with a reduction in the total fracture risk in both sexes (OR 0.95, 95% CI: 0.84- 1.08), either in cohort (OR 0.91; 95% CI: 0.79-1.05) or case-control studies (OR 1.09; 95% CI: 0.82-1.44), as well as separately in men (OR 0.87; 95% CI: 0.71-1.07) and women (OR 0.95; 95% CI: 0.80-1.13).
Conclusion: Higher milk consumption is not associated with fracture risk reduction and should not be recommended for fracture prevention.
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