血培养和肌钙蛋白检测在疑似细菌性贫血入院-基于临床试验的风险分层的例子。

Q3 Medicine

Acute Medicine Pub Date : 2022-01-01 DOI:10.52964/AMJA.0921

R Conway, D Byrne, D O'Riordan, B Silke

{"title":"血培养和肌钙蛋白检测在疑似细菌性贫血入院-基于临床试验的风险分层的例子。","authors":"R Conway, D Byrne, D O'Riordan, B Silke","doi":"10.52964/AMJA.0921","DOIUrl":null,"url":null,"abstract":"Aim: To investigate the clinical predictive value of troponin (hscTnT) and blood culture testing.Methods: We examined all medical admissions from 2011-2020. Prediction of 30-day in-hospital mortality, dependent on blood culture and hscTnT requests/results, was evaluated using multiple variable logistic regression. Length of stay was related to utilization of procedures/services with truncated Poisson regression.Results: There were 77,566 admissions in 42,325 patients. With both blood cultures and hscTnT requested, 30-day in-hospital mortality increased to 20.9% (95%CI: 19.7, 22.1) vs 8.9% (95%CI: 8.5, 9.4) for blood cultures alone and 2.3% (95%CI: 2.2, 2.4) with neither. Blood culture 3.93 (95%CI: 3.50, 4.42) or hsTnT requests 4.58 (95%CI: 4.10, 5.14) were prognostic.Conclusion: Blood culture and hscTnT requests and results predict worse outcomes.","PeriodicalId":39743,"journal":{"name":"Acute Medicine","volume":"21 4","pages":"176-181"},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Blood Culture and Troponin Testing in Suspected Bacteraemic Admissions - Example of Risk Stratification Based on Clinical Testing.\",\"authors\":\"R Conway, D Byrne, D O'Riordan, B Silke\",\"doi\":\"10.52964/AMJA.0921\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Aim: To investigate the clinical predictive value of troponin (hscTnT) and blood culture testing.Methods: We examined all medical admissions from 2011-2020. Prediction of 30-day in-hospital mortality, dependent on blood culture and hscTnT requests/results, was evaluated using multiple variable logistic regression. Length of stay was related to utilization of procedures/services with truncated Poisson regression.Results: There were 77,566 admissions in 42,325 patients. With both blood cultures and hscTnT requested, 30-day in-hospital mortality increased to 20.9% (95%CI: 19.7, 22.1) vs 8.9% (95%CI: 8.5, 9.4) for blood cultures alone and 2.3% (95%CI: 2.2, 2.4) with neither. Blood culture 3.93 (95%CI: 3.50, 4.42) or hsTnT requests 4.58 (95%CI: 4.10, 5.14) were prognostic.Conclusion: Blood culture and hscTnT requests and results predict worse outcomes.\",\"PeriodicalId\":39743,\"journal\":{\"name\":\"Acute Medicine\",\"volume\":\"21 4\",\"pages\":\"176-181\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acute Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52964/AMJA.0921\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acute Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52964/AMJA.0921","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 1

摘要

目的:探讨肌钙蛋白(hscTnT)及血培养检测的临床预测价值。方法:对2011-2020年所有住院患者进行调查。根据血培养和hscTnT请求/结果预测住院30天死亡率，采用多变量logistic回归进行评估。用截断泊松回归分析，住院时间与手术/服务的利用有关。结果:42,325例患者中有77,566例入院。同时要求血液培养和hscTnT, 30天住院死亡率增加到20.9% (95%CI: 19.7, 22.1)，而单独进行血液培养的死亡率为8.9% (95%CI: 8.5, 9.4)，两者均不进行的死亡率为2.3% (95%CI: 2.2, 2.4)。血培养3.93 (95%CI: 3.50, 4.42)或hsTnT要求4.58 (95%CI: 4.10, 5.14)为预后。结论:血培养和hscTnT要求和结果预示较差的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Blood Culture and Troponin Testing in Suspected Bacteraemic Admissions - Example of Risk Stratification Based on Clinical Testing.

Aim: To investigate the clinical predictive value of troponin (hscTnT) and blood culture testing.

Methods: We examined all medical admissions from 2011-2020. Prediction of 30-day in-hospital mortality, dependent on blood culture and hscTnT requests/results, was evaluated using multiple variable logistic regression. Length of stay was related to utilization of procedures/services with truncated Poisson regression.

Results: There were 77,566 admissions in 42,325 patients. With both blood cultures and hscTnT requested, 30-day in-hospital mortality increased to 20.9% (95%CI: 19.7, 22.1) vs 8.9% (95%CI: 8.5, 9.4) for blood cultures alone and 2.3% (95%CI: 2.2, 2.4) with neither. Blood culture 3.93 (95%CI: 3.50, 4.42) or hsTnT requests 4.58 (95%CI: 4.10, 5.14) were prognostic.

Conclusion: Blood culture and hscTnT requests and results predict worse outcomes.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Acute Medicine Medicine-Emergency Medicine

CiteScore

1.50

自引率

0.00%

发文量

期刊介绍： These are usually commissioned by the editorial team in accordance with a cycle running over several years. Authors wishing to submit a review relevant to Acute Medicine are advised to contact the editor before writing this. Unsolicited review articles received for consideration may be included if the subject matter is considered of interest to the readership, provided the topic has not already been covered in a recent edition. Review articles are usually 3000-5000 words and may include tables, pictures and other figures as required for the text. Include 3 or 4 ‘key points’ summarising the main teaching messages.