{"title":"干扰辐射对雄性大鼠学习记忆影响的评价。","authors":"Mehrnaz Yazdanpanahi, Abasaleh Namazi, Manzar Banoo Shojaeifard, Samaneh Nematolahi, Saeedeh Pourahmad","doi":"10.31661/jbpe.v0i0.2001-1049","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Previous studies shown that mobile phone can impairment of working memory in humans.</p><p><strong>Objective: </strong>In this study, the effect of radiofrequency radiation emitted from common mobile jammers have been studied on the learning and memory of rats.</p><p><strong>Material and methods: </strong>In this prospective study, 90 Sprague-Dawley rats, were divided into 9 groups (N=10): Control, Sham<sup>1st</sup> (exposed to a switched-off mobile jammer device at a distance of 50 or 100 cm/1 day, 2 hours), Sham<sup>2nd</sup> (similar to Sham<sup>1st</sup>, but for 14 days, 2 h/day), Experimental<sup>1st</sup> -50 cm/1 day &100 cm/1 day (exposed to a switched-on device at a distance of 50 or 100 cm for 2 hours), Experimental<sup>2nd</sup> (similar to experimental<sup>1st</sup>, but for 14 days, 2 h/day). The animals were tested for learning and memory the next day, by the shuttle box. The time that a rat took to enter the dark part was considered as memory.</p><p><strong>Results: </strong>Mean short-term memory was shorter in the experimental- 50 cm/1 day than control and sham- 50 cm/1 day (<i>P</i>=0.034), long-term memory was similar. Mean short- and long-term memory were similar in the experimental- 100 cm/1 day, control and sham- 100 cm/1 day (<i>P</i>>0.05). Mean short-term memory was similar in experimental- 50 cm/14 days, control, and sham- 50 cm/14 days (<i>P</i>=0.087), but long-term learning memory was shorter in the radiated group (<i>P</i>=0.038). Mean short- and long-term were similar among experimental-100 cm/14 days, control or sham 100 cm/14 days (<i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Rats exposed to jammer device showed dysfunction in short- and long-term memory, which shown the unfavorable effect of jammer on memory and learning. Our results indicated that the distance from radiation source was more important than the duration.</p>","PeriodicalId":38035,"journal":{"name":"Journal of Biomedical Physics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c1/8f/JBPE-13-29.PMC9923240.pdf","citationCount":"0","resultStr":"{\"title\":\"Evaluating the Effect of Jammer Radiation on Learning and Memory in Male Rats.\",\"authors\":\"Mehrnaz Yazdanpanahi, Abasaleh Namazi, Manzar Banoo Shojaeifard, Samaneh Nematolahi, Saeedeh Pourahmad\",\"doi\":\"10.31661/jbpe.v0i0.2001-1049\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Previous studies shown that mobile phone can impairment of working memory in humans.</p><p><strong>Objective: </strong>In this study, the effect of radiofrequency radiation emitted from common mobile jammers have been studied on the learning and memory of rats.</p><p><strong>Material and methods: </strong>In this prospective study, 90 Sprague-Dawley rats, were divided into 9 groups (N=10): Control, Sham<sup>1st</sup> (exposed to a switched-off mobile jammer device at a distance of 50 or 100 cm/1 day, 2 hours), Sham<sup>2nd</sup> (similar to Sham<sup>1st</sup>, but for 14 days, 2 h/day), Experimental<sup>1st</sup> -50 cm/1 day &100 cm/1 day (exposed to a switched-on device at a distance of 50 or 100 cm for 2 hours), Experimental<sup>2nd</sup> (similar to experimental<sup>1st</sup>, but for 14 days, 2 h/day). The animals were tested for learning and memory the next day, by the shuttle box. The time that a rat took to enter the dark part was considered as memory.</p><p><strong>Results: </strong>Mean short-term memory was shorter in the experimental- 50 cm/1 day than control and sham- 50 cm/1 day (<i>P</i>=0.034), long-term memory was similar. Mean short- and long-term memory were similar in the experimental- 100 cm/1 day, control and sham- 100 cm/1 day (<i>P</i>>0.05). Mean short-term memory was similar in experimental- 50 cm/14 days, control, and sham- 50 cm/14 days (<i>P</i>=0.087), but long-term learning memory was shorter in the radiated group (<i>P</i>=0.038). Mean short- and long-term were similar among experimental-100 cm/14 days, control or sham 100 cm/14 days (<i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Rats exposed to jammer device showed dysfunction in short- and long-term memory, which shown the unfavorable effect of jammer on memory and learning. Our results indicated that the distance from radiation source was more important than the duration.</p>\",\"PeriodicalId\":38035,\"journal\":{\"name\":\"Journal of Biomedical Physics and Engineering\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c1/8f/JBPE-13-29.PMC9923240.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Biomedical Physics and Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31661/jbpe.v0i0.2001-1049\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biomedical Physics and Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31661/jbpe.v0i0.2001-1049","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
背景:以往的研究表明,手机会损害人类的工作记忆。目的:研究普通移动干扰机射频辐射对大鼠学习记忆的影响。材料和方法:在这个前瞻性研究,90年Sprague-Dawley老鼠,被分成9组(N = 10):控制、Sham1st(暴露于关闭手机干扰机设备的距离50或100厘米/ 1天,2个小时),Sham2nd (Sham1st相似,但对于14天,2 h /天),Experimental1st -50厘米/ 1天&100厘米/ 1天(暴露于流行设备的距离50或100厘米2小时),Experimental2nd (Experimental1st相似,但对于14天,2 h /天)。第二天,通过穿梭箱对这些动物进行学习和记忆测试。老鼠进入黑暗区域的时间被认为是记忆。结果:实验组平均短期记忆为50 cm/1 d,短于对照组和假手术组平均50 cm/1 d (P=0.034),长时记忆差异无统计学意义。试验组平均短时记忆和长时记忆均为100 cm/1 d,对照组为100 cm/1 d,假手术组为100 cm/1 d (P>0.05)。试验组、对照组和假手术组的平均短期记忆与对照组(50 cm/14天)相似(P=0.087),但放射组的长期学习记忆较短(P=0.038)。试验组(100 cm/14)、对照组(100 cm/14)和假手术组(100 cm/14)的平均短期和长期差异无统计学意义(P>0.05)。结论:干扰器对大鼠的短期记忆和长期记忆均有影响,表明干扰器对大鼠的记忆和学习均有不利影响。我们的结果表明,距离辐射源比持续时间更重要。
Evaluating the Effect of Jammer Radiation on Learning and Memory in Male Rats.
Background: Previous studies shown that mobile phone can impairment of working memory in humans.
Objective: In this study, the effect of radiofrequency radiation emitted from common mobile jammers have been studied on the learning and memory of rats.
Material and methods: In this prospective study, 90 Sprague-Dawley rats, were divided into 9 groups (N=10): Control, Sham1st (exposed to a switched-off mobile jammer device at a distance of 50 or 100 cm/1 day, 2 hours), Sham2nd (similar to Sham1st, but for 14 days, 2 h/day), Experimental1st -50 cm/1 day &100 cm/1 day (exposed to a switched-on device at a distance of 50 or 100 cm for 2 hours), Experimental2nd (similar to experimental1st, but for 14 days, 2 h/day). The animals were tested for learning and memory the next day, by the shuttle box. The time that a rat took to enter the dark part was considered as memory.
Results: Mean short-term memory was shorter in the experimental- 50 cm/1 day than control and sham- 50 cm/1 day (P=0.034), long-term memory was similar. Mean short- and long-term memory were similar in the experimental- 100 cm/1 day, control and sham- 100 cm/1 day (P>0.05). Mean short-term memory was similar in experimental- 50 cm/14 days, control, and sham- 50 cm/14 days (P=0.087), but long-term learning memory was shorter in the radiated group (P=0.038). Mean short- and long-term were similar among experimental-100 cm/14 days, control or sham 100 cm/14 days (P>0.05).
Conclusion: Rats exposed to jammer device showed dysfunction in short- and long-term memory, which shown the unfavorable effect of jammer on memory and learning. Our results indicated that the distance from radiation source was more important than the duration.
期刊介绍:
The Journal of Biomedical Physics and Engineering (JBPE) is a bimonthly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research (experimental or theoretical) broadly concerned with the relationship of physics to medicine and engineering.