{"title":"COVID-19和心脏。","authors":"Roman Roy, Benedict McDonaugh, Kevin O'Gallagher","doi":"10.1093/bmb/ldac022","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>There is evidence for a bi-directional relationship between COVID-19 and the cardiovascular (CV) system.</p><p><strong>Source of data: </strong>Published literature.</p><p><strong>Areas of agreement: </strong>Pre-existing heart failure (HF) increases the risk of mortality with COVID-19. CV complications are recognized, including increased rates of acute coronary syndromes, HF, arrhythmia and myocarditis. Drugs targeting the angiotensin system are safe and may provide prognostic benefit.</p><p><strong>Areas of controversy: </strong>Vaccination as a cause of myocarditis remains a key area of contention.</p><p><strong>Growing points: </strong>As the pandemic progresses, we are gaining more data about the long-term effects of COVID-19 on the CV system: long COVID, and medium-to-long-term increases in CV risk.</p><p><strong>Areas timely for developing research: </strong>Large-scale longitudinal studies will shed light on long-term CV outcomes with COVID-19. Furthermore, the differential effects of COVID-19 variants on the CV system must be investigated.</p>","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":"144 1","pages":"4-11"},"PeriodicalIF":6.7000,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619476/pdf/ldac022.pdf","citationCount":"2","resultStr":"{\"title\":\"COVID-19 and the heart.\",\"authors\":\"Roman Roy, Benedict McDonaugh, Kevin O'Gallagher\",\"doi\":\"10.1093/bmb/ldac022\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>There is evidence for a bi-directional relationship between COVID-19 and the cardiovascular (CV) system.</p><p><strong>Source of data: </strong>Published literature.</p><p><strong>Areas of agreement: </strong>Pre-existing heart failure (HF) increases the risk of mortality with COVID-19. CV complications are recognized, including increased rates of acute coronary syndromes, HF, arrhythmia and myocarditis. Drugs targeting the angiotensin system are safe and may provide prognostic benefit.</p><p><strong>Areas of controversy: </strong>Vaccination as a cause of myocarditis remains a key area of contention.</p><p><strong>Growing points: </strong>As the pandemic progresses, we are gaining more data about the long-term effects of COVID-19 on the CV system: long COVID, and medium-to-long-term increases in CV risk.</p><p><strong>Areas timely for developing research: </strong>Large-scale longitudinal studies will shed light on long-term CV outcomes with COVID-19. Furthermore, the differential effects of COVID-19 variants on the CV system must be investigated.</p>\",\"PeriodicalId\":9280,\"journal\":{\"name\":\"British medical bulletin\",\"volume\":\"144 1\",\"pages\":\"4-11\"},\"PeriodicalIF\":6.7000,\"publicationDate\":\"2022-12-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619476/pdf/ldac022.pdf\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British medical bulletin\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/bmb/ldac022\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British medical bulletin","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/bmb/ldac022","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
Background: There is evidence for a bi-directional relationship between COVID-19 and the cardiovascular (CV) system.
Source of data: Published literature.
Areas of agreement: Pre-existing heart failure (HF) increases the risk of mortality with COVID-19. CV complications are recognized, including increased rates of acute coronary syndromes, HF, arrhythmia and myocarditis. Drugs targeting the angiotensin system are safe and may provide prognostic benefit.
Areas of controversy: Vaccination as a cause of myocarditis remains a key area of contention.
Growing points: As the pandemic progresses, we are gaining more data about the long-term effects of COVID-19 on the CV system: long COVID, and medium-to-long-term increases in CV risk.
Areas timely for developing research: Large-scale longitudinal studies will shed light on long-term CV outcomes with COVID-19. Furthermore, the differential effects of COVID-19 variants on the CV system must be investigated.
期刊介绍：
British Medical Bulletin is a multidisciplinary publication, which comprises high quality reviews aimed at generalist physicians, junior doctors, and medical students in both developed and developing countries.
Its key aims are to provide interpretations of growing points in medicine by trusted experts in the field, and to assist practitioners in incorporating not just evidence but new conceptual ways of thinking into their practice.
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