胶质瘤的外科治疗及进展。

IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY
Seminars in Neurology Pub Date : 2023-12-01 Epub Date: 2023-11-14 DOI:10.1055/s-0043-1776766
Andrew A Hardigan, Joshua D Jackson, Anoop P Patel
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引用次数: 0

摘要

高级别胶质瘤和低级别胶质瘤患者的护理需要神经外科医生、神经肿瘤学家、神经学家和其他从业人员之间的跨学科合作。在这篇综述中,我们旨在详细介绍神经胶质瘤的神经外科治疗的注意事项,方法和进展。我们描述了切除范围对高级别和低级别胶质瘤的影响,特别关注原发性和复发性胶质母细胞瘤。我们讨论了手术方法和辅助技术的进展,如术中成像和荧光引导手术,以最大限度地切除范围,同时最大限度地减少医源性神经功能障碍的可能性。最后,我们回顾了手术介导的治疗方法,而不是切除,并讨论了神经外科在跨学科胶质瘤管理的新兴范式转变中的作用,如连续组织采样和“机会之窗试验”。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical Management and Advances in the Treatment of Glioma.

The care of patients with both high-grade glioma and low-grade glioma necessitates an interdisciplinary collaboration between neurosurgeons, neuro-oncologists, neurologists and other practitioners. In this review, we aim to detail the considerations, approaches and advances in the neurosurgical care of gliomas. We describe the impact of extent-of-resection in high-grade and low-grade glioma, with particular focus on primary and recurrent glioblastoma. We address advances in surgical methods and adjunct technologies such as intraoperative imaging and fluorescence guided surgery that maximize extent-of-resection while minimizing the potential for iatrogenic neurological deficits. Finally, we review surgically-mediated therapies other than resection and discuss the role of neurosurgery in emerging paradigm-shifts in inter-disciplinary glioma management such as serial tissue sampling and "window of opportunity trials".

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来源期刊
Seminars in Neurology
Seminars in Neurology 医学-临床神经学
CiteScore
4.60
自引率
3.70%
发文量
65
审稿时长
6-12 weeks
期刊介绍: Seminars in Neurology is a review journal on current trends in the evaluation, diagnosis, and treatment of neurological diseases. Areas of coverage include multiple sclerosis, central nervous system infections, muscular dystrophy, neuro-immunology, spinal disorders, strokes, epilepsy, motor neuron diseases, movement disorders, higher cortical function, neuro-genetics and neuro-ophthamology. Each issue is presented under the direction of an expert guest editor, and invited contributors focus on a single, high-interest clinical topic. Up-to-the-minute coverage of the latest information in the field makes this journal an invaluable resource for neurologists and residents.
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