将研究基础设施纳入传染病监测行动:重点放在生物库上

IF 3.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Plebeian B. Medina , Jennifer Kealy , Zisis Kozlakidis
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引用次数: 0

摘要

21世纪头二十年的技术进步在许多方面深刻影响了医学研究,通过生物银行收集的大量人口、生物样本和数据集成为指导生物医学研究、药物开发和医疗实践的宝贵全球资源。然而,为了使生物银行最大限度地发挥其影响和其资源的科学覆盖范围,它们需要在一个复杂的基础设施和活动网络中行动。因此,出现了不同的方式,生物库,包括传染病生物库,可以作为基础设施(一部分)出现,与现有基础设施整合,或成为现有基础设施景观的一个独立但可互操作的组成部分。然而,迄今为止,对这种机制的理解和研究有限。这一观点旨在解决这一知识差距,并说明这些基础设施可以整合其活动的三种高级方法,并确定这样做的必要关键先决条件,同时借鉴具体的例子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Integrating research infrastructures into infectious diseases surveillance operations: Focus on biobanks

Technological advances in the first two decades of the 21st century have profoundly impacted medical research in many ways, with large population cohorts, biological sample collections and datasets through biobanks becoming valued global resources to guide biomedical research, drug development, and medical practice. However, in order for biobanks to maximize their impact and scientific reach of their resources, they would need to act within a complex network of infrastructures and activities. Therefore, different ways have emerged in which biobanks, including those for infectious diseases, can emerge as (part of) infrastructures, integrate within existing ones, or become an independent, yet an interoperable component of the existing infrastructural landscape. However, there has been a limited understanding and study of such mechanisms to date. This perspective aims to address this knowledge gap and illustrates these three high-level ways in which such infrastructures could integrate their activities and identifies the necessary key pre-conditions for doing so, while drawing from specific examples.

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来源期刊
Biosafety and Health
Biosafety and Health Medicine-Infectious Diseases
CiteScore
7.60
自引率
0.00%
发文量
116
审稿时长
66 days
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