Baojing Li, Peter Allebeck, Bo Burstöm, Anna-Karin Danielsson, Louisa Degenhardt, Terje A. Eikemo, Alize Ferrari, Ann Kristin Knudsen, Andreas Lundin, Hélio Manhica, John Newton, Harvey Whiteford, Pär Flodin, Hugo Sjöqvist, Emilie E. Agardh
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Hazard Ratios with 95% Confidence Intervals (CIs) were estimated with Cox proportional hazard models.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Low education increased the risk of substance use disorders and self-harm in all age-groups. Males aged 10–18 with low education had increased risks of ADHD and conduct disorders, and females a decreased risk of anorexia, bulimia and autism. Those aged 19–27 years had increased risks of anxiety and depression, and those aged 28–50 had increased risks of all mental disorders except anorexia and bulimia in males with Hazard Ratios ranging from 1.2 (95% CIs 1.0–1.3) for bipolar disorder to 5.4 (95% CIs 5.1–5.7) for drug use disorder. Females aged 51–70 years had increased risks of schizophrenia and autism.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Low education is associated with risk of most mental disorders, substance use disorders and self-harm in all age-groups, but especially among those aged 28–50 years.</p>\n </section>\n </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"32 4","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2023-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mpr.1964","citationCount":"1","resultStr":"{\"title\":\"Educational level and the risk of mental disorders, substance use disorders and self-harm in different age-groups: A cohort study covering 1,6 million subjects in the Stockholm region\",\"authors\":\"Baojing Li, Peter Allebeck, Bo Burstöm, Anna-Karin Danielsson, Louisa Degenhardt, Terje A. Eikemo, Alize Ferrari, Ann Kristin Knudsen, Andreas Lundin, Hélio Manhica, John Newton, Harvey Whiteford, Pär Flodin, Hugo Sjöqvist, Emilie E. Agardh\",\"doi\":\"10.1002/mpr.1964\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>To investigate the associations between low education and risk of mental disorders, substance use disorders and self-harm in different age-groups.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>All subjects in Stockholm born between 1931 and 1990 were linked to their own or their parent's highest education in 2000 and followed-up for these disorders in health care registers 2001–2016. Subjects were stratified into four age-groups: 10–18, 19–27, 28–50, and 51–70 years. 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引用次数: 1
摘要
目的:探讨不同年龄人群低文化程度与精神障碍、物质使用障碍和自残风险的关系。方法:所有出生于1931年至1990年的斯德哥尔摩受试者在2000年与自己或父母的最高教育程度相关，并在2001年至2016年期间在医疗保健登记册中随访这些疾病。受试者分为4个年龄组:10-18岁、19-27岁、28-50岁和51-70岁。采用Cox比例风险模型估计95%置信区间(ci)的风险比。结果:低教育水平增加了所有年龄组物质使用障碍和自残的风险。10-18岁受教育程度低的男性患多动症和行为障碍的风险增加，而女性患厌食症、贪食症和自闭症的风险降低。19-27岁的男性焦虑和抑郁风险增加，28-50岁的男性除厌食症和贪食症外所有精神障碍风险增加，风险比从双相情感障碍的1.2 (95% ci 1.0-1.3)到药物使用障碍的5.4 (95% ci 5.1-5.7)不等。51-70岁的女性患精神分裂症和自闭症的风险增加。结论:低教育程度与所有年龄组的大多数精神障碍、物质使用障碍和自残风险相关，但在28-50岁人群中尤为明显。
Educational level and the risk of mental disorders, substance use disorders and self-harm in different age-groups: A cohort study covering 1,6 million subjects in the Stockholm region
Objective
To investigate the associations between low education and risk of mental disorders, substance use disorders and self-harm in different age-groups.
Methods
All subjects in Stockholm born between 1931 and 1990 were linked to their own or their parent's highest education in 2000 and followed-up for these disorders in health care registers 2001–2016. Subjects were stratified into four age-groups: 10–18, 19–27, 28–50, and 51–70 years. Hazard Ratios with 95% Confidence Intervals (CIs) were estimated with Cox proportional hazard models.
Results
Low education increased the risk of substance use disorders and self-harm in all age-groups. Males aged 10–18 with low education had increased risks of ADHD and conduct disorders, and females a decreased risk of anorexia, bulimia and autism. Those aged 19–27 years had increased risks of anxiety and depression, and those aged 28–50 had increased risks of all mental disorders except anorexia and bulimia in males with Hazard Ratios ranging from 1.2 (95% CIs 1.0–1.3) for bipolar disorder to 5.4 (95% CIs 5.1–5.7) for drug use disorder. Females aged 51–70 years had increased risks of schizophrenia and autism.
Conclusion
Low education is associated with risk of most mental disorders, substance use disorders and self-harm in all age-groups, but especially among those aged 28–50 years.
期刊介绍：
The International Journal of Methods in Psychiatric Research (MPR) publishes high-standard original research of a technical, methodological, experimental and clinical nature, contributing to the theory, methodology, practice and evaluation of mental and behavioural disorders. The journal targets in particular detailed methodological and design papers from major national and international multicentre studies. There is a close working relationship with the US National Institute of Mental Health, the World Health Organisation (WHO) Diagnostic Instruments Committees, as well as several other European and international organisations.
MPR aims to publish rapidly articles of highest methodological quality in such areas as epidemiology, biostatistics, generics, psychopharmacology, psychology and the neurosciences. Articles informing about innovative and critical methodological, statistical and clinical issues, including nosology, can be submitted as regular papers and brief reports. Reviews are only occasionally accepted.
MPR seeks to monitor, discuss, influence and improve the standards of mental health and behavioral neuroscience research by providing a platform for rapid publication of outstanding contributions. As a quarterly journal MPR is a major source of information and ideas and is an important medium for students, clinicians and researchers in psychiatry, clinical psychology, epidemiology and the allied disciplines in the mental health field.
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