关于生物化学课程中Michaelis-Menten动力学教学的建议

IF 1.2 4区教育学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biochemistry and Molecular Biology Education Pub Date : 2022-11-07 DOI:10.1002/bmb.21689

Andrew J. Howard

引用次数: 0

摘要

大多数教科书和讲师使用方程v = Vmax[S]/(Km + [S])来介绍Michaelis-Menten动力学。用稍微不同的形式表示这种关系有好处，即v = Vmax/{1 + (Km/[S])}。我们阐明了单底物反应的优点，并将形式主义扩展到包括三种双底物反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A recommendation on the teaching of Michaelis–Menten kinetics in biochemistry courses

Most textbooks and lecturers present Michaelis–Menten kinetics using the equation v = V_max[S]/(K_m + [S]). There are advantages to presenting this relationship in a slightly different form, namely v = V_max/{1 + (K_m/[S])}. We articulate advantages for single-substrate reactions and extend the formalism to include the three classes of bi-substrate reactions.

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来源期刊

Biochemistry and Molecular Biology Education 生物-生化与分子生物学

CiteScore

2.60

自引率

14.30%

发文量

审稿时长

6-12 weeks

期刊介绍： The aim of BAMBED is to enhance teacher preparation and student learning in Biochemistry, Molecular Biology, and related sciences such as Biophysics and Cell Biology, by promoting the world-wide dissemination of educational materials. BAMBED seeks and communicates articles on many topics, including: Innovative techniques in teaching and learning. New pedagogical approaches. Research in biochemistry and molecular biology education. Reviews on emerging areas of Biochemistry and Molecular Biology to provide background for the preparation of lectures, seminars, student presentations, dissertations, etc. Historical Reviews describing "Paths to Discovery". Novel and proven laboratory experiments that have both skill-building and discovery-based characteristics. Reviews of relevant textbooks, software, and websites. Descriptions of software for educational use. Descriptions of multimedia materials such as tutorials on various aspects of biochemistry and molecular biology.