原发性食管淋巴瘤:来自沙特阿拉伯西部两家三级医院的组织病理学经验。

IF 2 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY
Jaudah Al-Maghrabi, Sahar Al-Maghrabi
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引用次数: 0

摘要

背景:原发性食管淋巴瘤(PEL)是一种罕见的疾病。本研究的目的是记录沙特阿拉伯王国西部地区两家三级医院的PEL的临床病理特征。方法:检索2002年5月至2022年6月诊断的所有PELs。复习组织病理学和免疫组织化学切片。在选定的病例中进行额外的免疫组织化学染色。收集随访数据。结果:两家医院记录的PEL病例仅有8例。患者年龄50 ~ 74岁(中位62岁,平均62.5岁)。男性6例(80%),女性2例(20%)。所有患者均无免疫功能低下或感染人类免疫缺陷病毒(HIV)。临床表现为吞咽困难和体重减轻。弥漫性大b细胞淋巴瘤(DLBCL) 6例,低级别粘膜相关淋巴组织淋巴瘤2例。结论:PEL是一种极为罕见的疾病,男性多见。DLBCL是我们社区最常见的病理类型。该系列与免疫状态或HIV感染无关。临床表现为典型的吞咽困难伴体重减轻。进一步报告PEL病例可能有助于解释这种疾病并改善其诊断和管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Primary Esophageal Lymphoma: A Histopathological Experience from Two Tertiary Hospitals, Western Saudi Arabia.

Primary Esophageal Lymphoma: A Histopathological Experience from Two Tertiary Hospitals, Western Saudi Arabia.

Background: Primary esophageal lymphoma (PEL) is a rare disorder. The objective of this study was to document the clinicopathological features of PEL at two tertiary hospitals in the western region of the Kingdom of Saudi Arabia.

Methods: All PELs diagnosed between May 2002 and June 2022 were retrieved. Histopathological and immunohistochemical slides were reviewed. Additional immunohistochemistry stains were performed in selected cases. Follow-up data were collected.

Results: There were only eight cases of PEL in the records of the two hospitals. The age of the patients ranged between 50 and 74 years (median 62 years and mean 62.5 years). There were six males (80%) and two females (20%). None of the patients were immunocompromised or had human immunodeficiency virus (HIV) infection. The clinical manifestation included dysphagia and loss of weight. Six cases were diffuse large B-cell lymphoma (DLBCL), and two were low-grade mucosa-associated lymphoid tissue lymphoma.

Conclusion: PEL is an extremely rare disease with male predominance. DLBCL is the most common pathological type in our community. There was no relation to immune status or HIV infection in this series. Clinical presentations were typically dysphagia with weight loss. Further reporting of PEL cases might help explain this disease and improve its diagnosis and management.

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来源期刊
Gastroenterology Research and Practice
Gastroenterology Research and Practice GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.40
自引率
0.00%
发文量
91
审稿时长
1 months
期刊介绍: Gastroenterology Research and Practice is a peer-reviewed, Open Access journal which publishes original research articles, review articles and clinical studies based on all areas of gastroenterology, hepatology, pancreas and biliary, and related cancers. The journal welcomes submissions on the physiology, pathophysiology, etiology, diagnosis and therapy of gastrointestinal diseases. The aim of the journal is to provide cutting edge research related to the field of gastroenterology, as well as digestive diseases and disorders. Topics of interest include: Management of pancreatic diseases Third space endoscopy Endoscopic resection Therapeutic endoscopy Therapeutic endosonography.
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