滥用史是否可以通过冲动介导的效应预测暴饮暴食的饮食失调?一项法国纵向研究。

IF 4.1 2区 医学 Q2 NEUROSCIENCES
Clémence Cabelguen, Anaïs Saillard, Antoine Vanier, Manuel Laslandes, Juliette Leboucher, Morgane Rousselet, Elsa Thiabaud, Marie Grall-Bronnec, Gaëlle Challet-Bouju
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引用次数: 2

摘要

背景:近年来,许多研究探讨了冲动、虐待史、饮食失调与暴食发作(EDBE)及其严重程度之间的关系。然而,与EDBE成功临床结果相关的因素仍然未知。我们的研究旨在通过冲动介导的效应来验证滥用史与EDBE不成功的临床结果相关的假设。方法:我们评估了年龄大于15岁3个月的EDBE患者在纳入和1年时的情况。康复的定义是1年内没有饮食失调。通过结构方程模型进行中介分析。结果:我们纳入186例患者(54%为神经性贪食症,29%为神经性厌食症暴食/泻型,17%为暴食症);179例(96%)为女性。三分之一(n = 63)的患者报告有虐待史,20%的患者(n = 38)康复。与我们的假设相反,滥用史与1年内未恢复EDBE无关。对康复不利的因素有焦虑障碍(比值比[OR] 0.41)、呕吐(OR 0.39)、身体多动(OR 0.29)、消极急迫感和缺乏毅力(两者比值比均为0.85)。只有积极的紧迫感与恢复呈正相关(OR 1.25)。局限性:我们排除了219例1年随访失败的患者。结论:我们的研究结果可能有助于解构创伤性事件可能影响饮食失调成功治疗过程的经验信念。高度的积极紧迫感可能与更容易接受护理有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Is history of abuse predictive of eating disorders with binge-eating episodes through an effect mediated by impulsivity? A French longitudinal study.

Is history of abuse predictive of eating disorders with binge-eating episodes through an effect mediated by impulsivity? A French longitudinal study.

Background: In recent years, many studies have explored the associations among impulsivity, history of abuse, the emergence of eating disorders with episodes of binge eating (EDBE) and their severity. Nevertheless, factors associated with successful clinical outcomes of EDBE are still unknown. Our study aimed to test the hypothesis that a history of abuse is associated with unsuccessful clinical outcomes of EDBE through an effect mediated by impulsivity.

Methods: We assessed patients older than 15 years, 3 months with EDBE at inclusion and at 1 year. Recovery was defined as the absence of eating disorders at 1 year. A mediation analysis was performed by means of structural equation modelling.

Results: We included 186 patients in our analyses (54% bulimia nervosa, 29% anorexia nervosa binge eating/purging type and 17% binge-eating disorder); 179 (96%) were female. One-third (n = 63) of patients reported a history of abuse, and recovery was observed for 20% of the sample (n = 38). Contrary to our assumption, a history of abuse was not associated with the absence of recovery of EDBE at 1 year. Factors unfavourable for achieving recovery were anxiety disorders (odds ratio [OR] 0.41), vomiting (OR 0.39), physical hyperactivity (OR 0.29), negative urgency and a lack of perseverance (OR 0.85 for both). Only positive urgency was positively associated with recovery (OR 1.25).

Limitations: We excluded 219 patients lost to the 1-year follow-up.

Conclusion: Our findings may help to deconstruct the empirical belief that traumatic events may interfere with the successful course of treatment for eating disorders. A high level of positive urgency may be associated with more receptivity to care.

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来源期刊
CiteScore
6.80
自引率
2.30%
发文量
51
审稿时长
2 months
期刊介绍: The Journal of Psychiatry & Neuroscience publishes papers at the intersection of psychiatry and neuroscience that advance our understanding of the neural mechanisms involved in the etiology and treatment of psychiatric disorders. This includes studies on patients with psychiatric disorders, healthy humans, and experimental animals as well as studies in vitro. Original research articles, including clinical trials with a mechanistic component, and review papers will be considered.
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