类固醇激素信号：我们可以从昆虫模型中学到什么。

4区医学 Q3 Biochemistry, Genetics and Molecular Biology

Vitamins and Hormones Pub Date : 2023-01-01 Epub Date: 2023-02-06 DOI:10.1016/bs.vh.2022.12.006

Naoki Okamoto, Daiki Fujinaga, Naoki Yamanaka

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引用次数: 0

摘要

蜕皮甾体是节肢动物体内的一组类固醇激素，在其一生中具有多效性功能。昆虫的蜕皮甾体研究为我们目前对后生动物类固醇激素信号的理解做出了重大贡献，但我们能在多大程度上将我们在昆虫中的发现推广到其他系统，如哺乳动物？在本章中，我们从多个角度比较了昆虫和哺乳动物的类固醇激素信号，并讨论了这两个谱系之间的异同。我们还强调了后生动物类固醇激素生物学的一些研究不足的领域和遗留问题，并提出了未来潜在的研究方向。

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Steroid hormone signaling: What we can learn from insect models.

Ecdysteroids are a group of steroid hormones in arthropods with pleiotropic functions throughout their life history. Ecdysteroid research in insects has made a significant contribution to our current understanding of steroid hormone signaling in metazoans, but how far can we extrapolate our findings in insects to other systems, such as mammals? In this chapter, we compare steroid hormone signaling in insects and mammals from multiple perspectives and discuss similarities and differences between the two lineages. We also highlight a few understudied areas and remaining questions of steroid hormone biology in metazoans and propose potential future research directions.

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来源期刊

Vitamins and Hormones 医学-内分泌学与代谢

CiteScore

3.80

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.