{"title":"第二波COVID-19顺势疗法药物:预后因素研究","authors":"Raj Kumar Manchanda, Anjali Miglani, Moumita Chakraborty, Amrit Kalsi, Baljeet Singh Meena, Prabhjeet Kaur, Beenu Saini, Amit Arora, Cheshta Nagrath, Jithesh Thavarayil Kannoth, Ram Kumar Kudiyarasu, Rahul Vardaan, Smita Brahmachari, Yogesh Kumar, B Amitav, Pramod Konthembath, Ankit Gupta, Suresh Kumar Lolugu, Pawan Goel, Shelly Arora, Shirin Balan, Kavita Sharma, Anu Chawla, Malaya Kumar Ray, Vineetha Susan Jacob, Udesh Kumar, Vikas Kumar Verma, Rahul Kumar Singh, Abishes Saha, Manjula Ghuliani, Paramjeet Kaur, Shruti Gora, Meeta Gupta, Brender Sharma, Lex Rutten","doi":"10.1055/s-0042-1748881","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The clinical profile and course of COVID-19 evolved perilously in a second wave, leading to the use of various treatment modalities that included homeopathy. This prognostic factor research (PFR) study aimed to identify clinically useful homeopathic medicines in this second wave.</p><p><strong>Methods: </strong>This was a retrospective, multi-centred observational study performed from March 2021 to May 2021 on confirmed COVID-19 cases who were either in home isolation or at COVID Care Centres in Delhi, India. The data were collected from integrated COVID Care Centres where homeopathic medicines were prescribed along with conventional treatment. Only those cases that met a set of selection criteria were considered for analysis. The likelihood ratio (LR) was calculated for the frequently occurring symptoms of the prescribed medicines. An LR of 1.3 or greater was considered meaningful.</p><p><strong>Results: </strong>Out of 769 confirmed COVID-19 cases reported, 514 cases were selected for analysis, including 467 in home isolation. The most common complaints were cough, fever, myalgia, sore throat, loss of taste and/or smell, and anxiety. Most cases improved and there was no adverse reaction. Certain new symptoms, e.g., headache, dryness of mouth and conjunctivitis, were also seen. Thirty-nine medicines were prescribed, the most frequent being <i>Bryonia alba</i> followed by <i>Arsenicum album</i>, <i>Pulsatilla nigricans</i>, <i>Belladonna</i>, <i>Gelsemium sempervirens</i>, <i>Hepar sulphuris</i>, <i>Phosphorus</i>, <i>Rhus toxicodendron</i> and <i>Mercurius solubilis</i>. By calculating LR, the prescribing indications of these nine medicines were ascertained.</p><p><strong>Conclusion: </strong>Add-on use of homeopathic medicines has shown encouraging results in the second wave of COVID-19 in integrated care facilities. Further COVID-related research is required to be undertaken on the most commonly prescribed medicines.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":"112 1","pages":"12-21"},"PeriodicalIF":1.2000,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Homeopathic Medicines in Second Wave of COVID-19: Prognostic Factor Research.\",\"authors\":\"Raj Kumar Manchanda, Anjali Miglani, Moumita Chakraborty, Amrit Kalsi, Baljeet Singh Meena, Prabhjeet Kaur, Beenu Saini, Amit Arora, Cheshta Nagrath, Jithesh Thavarayil Kannoth, Ram Kumar Kudiyarasu, Rahul Vardaan, Smita Brahmachari, Yogesh Kumar, B Amitav, Pramod Konthembath, Ankit Gupta, Suresh Kumar Lolugu, Pawan Goel, Shelly Arora, Shirin Balan, Kavita Sharma, Anu Chawla, Malaya Kumar Ray, Vineetha Susan Jacob, Udesh Kumar, Vikas Kumar Verma, Rahul Kumar Singh, Abishes Saha, Manjula Ghuliani, Paramjeet Kaur, Shruti Gora, Meeta Gupta, Brender Sharma, Lex Rutten\",\"doi\":\"10.1055/s-0042-1748881\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The clinical profile and course of COVID-19 evolved perilously in a second wave, leading to the use of various treatment modalities that included homeopathy. This prognostic factor research (PFR) study aimed to identify clinically useful homeopathic medicines in this second wave.</p><p><strong>Methods: </strong>This was a retrospective, multi-centred observational study performed from March 2021 to May 2021 on confirmed COVID-19 cases who were either in home isolation or at COVID Care Centres in Delhi, India. The data were collected from integrated COVID Care Centres where homeopathic medicines were prescribed along with conventional treatment. Only those cases that met a set of selection criteria were considered for analysis. The likelihood ratio (LR) was calculated for the frequently occurring symptoms of the prescribed medicines. An LR of 1.3 or greater was considered meaningful.</p><p><strong>Results: </strong>Out of 769 confirmed COVID-19 cases reported, 514 cases were selected for analysis, including 467 in home isolation. The most common complaints were cough, fever, myalgia, sore throat, loss of taste and/or smell, and anxiety. Most cases improved and there was no adverse reaction. Certain new symptoms, e.g., headache, dryness of mouth and conjunctivitis, were also seen. Thirty-nine medicines were prescribed, the most frequent being <i>Bryonia alba</i> followed by <i>Arsenicum album</i>, <i>Pulsatilla nigricans</i>, <i>Belladonna</i>, <i>Gelsemium sempervirens</i>, <i>Hepar sulphuris</i>, <i>Phosphorus</i>, <i>Rhus toxicodendron</i> and <i>Mercurius solubilis</i>. By calculating LR, the prescribing indications of these nine medicines were ascertained.</p><p><strong>Conclusion: </strong>Add-on use of homeopathic medicines has shown encouraging results in the second wave of COVID-19 in integrated care facilities. Further COVID-related research is required to be undertaken on the most commonly prescribed medicines.</p>\",\"PeriodicalId\":13227,\"journal\":{\"name\":\"Homeopathy\",\"volume\":\"112 1\",\"pages\":\"12-21\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2023-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Homeopathy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0042-1748881\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INTEGRATIVE & COMPLEMENTARY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Homeopathy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/s-0042-1748881","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
Homeopathic Medicines in Second Wave of COVID-19: Prognostic Factor Research.
Background: The clinical profile and course of COVID-19 evolved perilously in a second wave, leading to the use of various treatment modalities that included homeopathy. This prognostic factor research (PFR) study aimed to identify clinically useful homeopathic medicines in this second wave.
Methods: This was a retrospective, multi-centred observational study performed from March 2021 to May 2021 on confirmed COVID-19 cases who were either in home isolation or at COVID Care Centres in Delhi, India. The data were collected from integrated COVID Care Centres where homeopathic medicines were prescribed along with conventional treatment. Only those cases that met a set of selection criteria were considered for analysis. The likelihood ratio (LR) was calculated for the frequently occurring symptoms of the prescribed medicines. An LR of 1.3 or greater was considered meaningful.
Results: Out of 769 confirmed COVID-19 cases reported, 514 cases were selected for analysis, including 467 in home isolation. The most common complaints were cough, fever, myalgia, sore throat, loss of taste and/or smell, and anxiety. Most cases improved and there was no adverse reaction. Certain new symptoms, e.g., headache, dryness of mouth and conjunctivitis, were also seen. Thirty-nine medicines were prescribed, the most frequent being Bryonia alba followed by Arsenicum album, Pulsatilla nigricans, Belladonna, Gelsemium sempervirens, Hepar sulphuris, Phosphorus, Rhus toxicodendron and Mercurius solubilis. By calculating LR, the prescribing indications of these nine medicines were ascertained.
Conclusion: Add-on use of homeopathic medicines has shown encouraging results in the second wave of COVID-19 in integrated care facilities. Further COVID-related research is required to be undertaken on the most commonly prescribed medicines.
期刊介绍：
Homeopathy is an international peer-reviewed journal aimed at improving the fundamental understanding and clinical practice of homeopathy by publishing relevant high-quality original research articles, reviews, and case reports. It also promotes commentary and debate on matters of topical interest in homeopathy.
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