醛肟的直接合成：钌催化醇与盐酸羟胺的偶联

IF 3.5 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemistry - An Asian Journal Pub Date : 2023-09-06 DOI:10.1002/asia.202300678

Deepsagar Manikpuri, Raman Vijaya Sankar, Prof. Dr. Chidambaram Gunanathan

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引用次数: 0

摘要

报道了一种由醇和羟胺盐酸盐直接合成肟的催化方法。该反应由钌钳形催化剂催化，该催化剂氧化醇，涉及胺酰胺金属配体的配合原位形成的醛与羟胺缩合以递送肟。值得注意的是，该反应仅需要催化剂和碱；水和释放的氢气是唯一的副产品，这使得该协议具有吸引力，对环境无害。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Direct Synthesis of Aldoximes: Ruthenium-Catalyzed Coupling of Alcohols and Hydroxylamine Hydrochloride

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Direct Synthesis of Aldoximes: Ruthenium-Catalyzed Coupling of Alcohols and Hydroxylamine Hydrochloride

A catalytic method for the direct synthesis of oximes from alcohols and hydroxyl amine hydrochloride salt is reported. The reaction is catalyzed by a ruthenium pincer catalyst, which oxidizes alcohols involving amine-amide metal-ligand cooperation, and the in situ formed aldehydes condense with hydroxyl amine to deliver the oximes. Notably, the reaction requires only a catalyst and base; water and liberated hydrogen are the only byproducts, making this protocol attractive and environmentally benign.

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来源期刊

Chemistry - An Asian Journal 化学-化学综合

CiteScore

7.00

自引率

2.40%

发文量

535

审稿时长

1.3 months

期刊介绍： Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics. Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews. A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal. Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).