巩膜睫状沟脉络膜上微管技术治疗黑人和拉丁裔青光眼患者的实际疗效:一项为期1年的回顾性研究。

IF 2.3 Q2 OPHTHALMOLOGY
Daniel Laroche, Gideon Nkrumah, Chester Ng
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引用次数: 1

摘要

背景:脉络膜上手术可以降低眼压和药物使用。目前市场上还没有商业化的脉络膜上产品。在这里,我们报告了一种新的睫状沟脉络膜上微管技术1年的结果。目的:探讨巩膜睫状沟脉络膜上微管技术在黑人和非裔拉丁裔青光眼患者对局部高眼压药物治疗的实际疗效。方法:回顾性非比较单中心研究36例黑人和非裔拉丁人青光眼和假性晶状体患者,这些患者在一次单独手术中接受了巩膜睫状沟上微管手术治疗青光眼。研究参数为用药次数、视力(VA)、眼压(IOP)、视野平均偏差(VF)。成功被定义为(a) IOP≤15 mmHg和或小于或等于20% IOP降低和(b)药物数量减少。我们采用配对t检验比较基线和随访参数。结果:我们共回顾了36例接受该手术的患者。其中20人在12个月的随访中取得了成功。平均用药次数由术前4.2±1.0次减少至12个月后的2.4±1.7次(p = 0.021),其中5例患者为免用药。IOP由21±8.2 mmHg降至13.5±4.4 mmHg (p = 0.032)。在随访12个月的20例患者中,VA保持稳定在Log Mar 0.62±0.6-0.46±0.6 (p = 0.052)。手术成功(无进一步干预)患者的VF在6-12个月时保持稳定,基线平均偏差为-16.53±10.04至-16.82±9.80 dB。不良反应是短暂的,包括IOP尖峰、低眼压、前房积血和角膜水肿,这些都得到了治疗和解决。结论:这项为期12个月的回顾性研究表明,巩膜上睫状沟微管手术可降低青光眼假性晶状体患者的IOP和药物负担。然而,尽管取得了一些成功,仍应监测眼压峰值、可能的管梗阻以及是否需要进行额外的青光眼手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Real-world efficacy of the intrascleral ciliary sulcus suprachoroidal microtube technique in Black and Afro-Latinx patients with glaucoma: a 1-year retrospective study.

Real-world efficacy of the intrascleral ciliary sulcus suprachoroidal microtube technique in Black and Afro-Latinx patients with glaucoma: a 1-year retrospective study.

Real-world efficacy of the intrascleral ciliary sulcus suprachoroidal microtube technique in Black and Afro-Latinx patients with glaucoma: a 1-year retrospective study.

Real-world efficacy of the intrascleral ciliary sulcus suprachoroidal microtube technique in Black and Afro-Latinx patients with glaucoma: a 1-year retrospective study.
Background: Suprachoroidal surgery can lower intraocular pressure and medication use. There is currently no commercial suprachoroidal product on the market. Here, we report our 1 year results of a novel ciliary sulcus suprachoroidal microtube technique. Purpose: To determine the real-world efficacy of intrascleral ciliary sulcus suprachoroidal microtube technique in Black and Afro-Latinx patients with glaucoma refractory to topical ocular hypertensive medications. Methods: A retrospective non-comparative single center study of 36 Black and Afro-Latinx patients with glaucoma and pseudophakia who underwent intrascleral ciliary sulcus suprachoroidal microtube surgery for glaucoma as a stand-alone procedure at a single practice. Investigated parameters were number of medications, visual acuity (VA), intraocular pressure (IOP), mean deviation on visual field (VF) test. Success was defined as (a) IOP ⩽ 15 mmHg and or ⩾ 20% reduction in IOP and (b) a reduction in number of medications. We used paired t-test to compare baseline and follow-up parameters. Results: We reviewed a total of 36 patients who had undergone the procedure. Twenty had success with 12-month follow-up in the study. The mean number of medications decreased significantly from 4.2 ± 1.0 preoperatively to 2.4 ± 1.7 in 12 months (p = 0.021) with five patients being medication free. In addition, the IOP decreased significantly from 21 ± 8.2 to 13.5 ± 4.4 mmHg (p = 0.032). In the 20 patients who had 12-month follow-up, the VA remained stable from Log Mar 0.62 ± 0.6–0.46 ± 0.6 (p = 0.052). VF in patients with successful procedure (no further interventions) remained stable from baseline mean deviation of –16.53 ± 10.04 to –16.82 ± 9.80 dB at 6–12 months. Adverse effects were transient and included IOP spike, hypotony, hyphema, and cornea edema that were treated and resolved. Conclusions: This 12-month retrospective study demonstrated that intrascleral ciliary sulcus suprachoroidal microtube surgery can reduce IOP and medication burden in pseudophakic patients with glaucoma. However, despite several successes, surveillance should take place for IOP spikes, possible tube obstruction, and need for additional glaucoma surgery.
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CiteScore
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44
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