肾上腺淋巴瘤:病例报告和小型回顾。

IF 2.1 Q3 ENDOCRINOLOGY & METABOLISM
Emad Mofid Nassif Rezkallah, Ragai Sobhi Hanna, Wael Magdy Elsaify
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引用次数: 0

摘要

简介:肾上腺淋巴瘤是一种罕见的疾病,可能发生在两种形式之一;原发性肾上腺淋巴瘤(PAL)或继发于系统性淋巴瘤。原发性肾上腺淋巴瘤是一种非常罕见的诊断,最常见的组织学类型是弥漫性大b细胞非霍奇金淋巴瘤。目的:在本研究中,我们报告了原发性和继发性肾上腺淋巴瘤的两个例子。此外,我们还包括了关于这一罕见表现的文献综述。患者和方法:我们回顾性分析了本院所有确诊为肾上腺淋巴瘤的患者。我们主要代表两个最具挑战性的情况下,肾上腺手术需要确认诊断。我们纳入了一篇关于肾上腺淋巴瘤病例临床表现和治疗的文献综述(PubMed数据库:1990 - 2020)。结果:本院17例肾上腺淋巴瘤患者;其中16例继发累及肾上腺,1例为原发性肾上腺淋巴瘤。肾上腺淋巴瘤患者主要表现为发热、腰痛和/或肾上腺功能不全的症状。原发性肾上腺淋巴瘤在计算机断层扫描(CT)或磁共振成像(MRI)上通常表现为低密度的异质性复杂大肿块;然而,没有病理特征来诊断PAL,只能通过组织活检来确诊。化疗通常是淋巴瘤的标准治疗方法,而手术的作用有限。结论:这些罕见病例的预后通常很差,只有约三分之一的患者在治疗后部分或完全缓解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Adrenal Lymphoma: Case Reports and Mini-review.

Adrenal Lymphoma: Case Reports and Mini-review.

Adrenal Lymphoma: Case Reports and Mini-review.

Adrenal Lymphoma: Case Reports and Mini-review.

Introduction: Adrenal lymphoma is a rare condition which may occur in one of two forms; either as primary adrenal lymphoma (PAL), or secondary to a systemic lymphoma. Primary adrenal lymphoma is a very rare diagnosis and the most common histological pattern is diffuse large B-cell non‑Hodgkin lymphoma.

Objectives: In this study, we represent two examples of adrenal lymphoma, primary and secondary. In addition, we have included a mini-review of the literature regarding this rare presentation.

Patients and methods: We retrospectively reviewed all patients who were diagnosed with adrenal lymphoma in our hospital. We represent mainly the most two challenging cases where adrenal surgery was required to confirm the diagnosis. We have included a mini-review of the literature (PubMed data base: 1990 - 2020) on the clinical presentation and management of adrenal lymphoma cases.

Results: Seventeen patients had adrenal lymphoma in our hospital; 16 of them had secondary involvement of the adrenal gland, while the last one had primary adrenal lymphoma. Patients with adrenal lymphoma mainly present with fever, lumbar pain, and/or symptoms of adrenal insufficiency. Primary adrenal lymphoma usually appears as heterogeneous complex large masses with low density on computerized tomography (CT) scan or magnetic resonance imaging (MRI); however, there is no pathognomonic features to diagnose PAL. The diagnosis is confirmed only with tissue biopsy. Chemotherapy is generally the standard treatment for lymphoma, while the role of surgery is limited.

Conclusions: The prognosis of these rare cases is generally poor with only about a third of patients achieving partial or complete remission following treatment.

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来源期刊
CiteScore
3.10
自引率
4.80%
发文量
0
期刊介绍: The aim of the International Journal of Endocrinology and Metabolism (IJEM) is to increase knowledge, stimulate research in the field of endocrinology, and promote better management of patients with endocrinological disorders. To achieve this goal, the journal publishes original research papers on human, animal and cell culture studies relevant to endocrinology.
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