马齿苋新生物碱及其抗炎活性研究。

IF 1.8 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences Pub Date : 2023-09-13 Print Date: 2023-11-27 DOI:10.1515/znc-2022-0245

Junjie Yao, Lina Wang, Peishan Liu, Mingyang Song, Jiayin Tian, Fan He, Xixiang Ying

引用次数: 0

摘要

从马蹄苋中分离到一种新的异吲哚生物碱- 6-羟基-2-(4′′-羟基-3′-甲氧基苯基)-4-(4′-羟基-3′-甲氧基苯基)-7-甲氧基- 1h -苯并[f]异吲哚-1,3(2H)-二酮，命名为oleraisoindole B。利用NMR和UHPLC-ESI-Q-TOF/MS对其结构进行了鉴定，发现其在5 μM范围内具有抗炎活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A new alkaloid from Portulaca oleracea L. with its anti-inflammatory activity.

A new isoindole alkaloid, 6-hydroxy-2-(4'''-hydroxy-3'''-methoxyphenethyl)-4-(4'-hydroxy-3'-methoxyphenyl)-7-methoxy-1H-benzo[f]isoindole-1,3(2H)-dione, named oleraisoindole B was isolated from Portulaca oleracea L., its structure was elucidated using NMR and UHPLC-ESI-Q-TOF/MS spectroscopic methods, and presented anti-inflammatory activity at 5 μM.

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来源期刊

Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences 生物-生化与分子生物学

CiteScore

4.10

自引率

5.00%

发文量

期刊介绍： A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) is an international scientific journal and a community resource for the emerging field of natural and natural-like products. The journal publishes original research on the isolation (including structure elucidation), bio-chemical synthesis and bioactivities of natural products, their biochemistry, pharmacology, biotechnology, and their biological activity and innovative developed computational methods for predicting the structure and/or function of natural products. A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) welcomes research papers in fields on the chemistry-biology boundary which address scientific ideas and approaches to generate and understand natural compounds on a molecular level and/or use them to stimulate and manipulate biological processes.